3514-05A
Human Carotid Artery Smooth Muscle Cells: HCtASMC, adult
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About This Item
NACRES:
NA.81
UNSPSC Code:
41106514
Biological source:
human carotid artery (normal)
Growth mode:
Adherent
Relevant disease(s):
stroke; cardiovascular diseases
biological source
human carotid artery (normal)
packaging
pkg of 500,000 cells
manufacturer/tradename
Cell Applications, Inc
growth mode
Adherent
karyotype
23
technique(s)
cell culture | mammalian: suitable
relevant disease(s)
stroke; cardiovascular diseases
storage temp.
−196°C
Quality Level
Application
cardiovascluar function, transfer of oxygenated blood to skull, brain, neck, face, effects of drugs
Biochem/physiol Actions
Artery
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
General description
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Human Carotid Artery Smooth Muscle Cells (HCtASMC) provide a useful in vitro system to study all aspects of cardiovascular function and disease, especially those related to mechanisms of hyperplasia and hypertrophy of intimal smooth muscle cells leading to vascular occlusion in atherosclerosis and stent restenosis.Characterization: positive for smooth muscle cell specific alpha-actin expression.
Human Carotid Artery Smooth Muscle Cells (HCtASMC) provide a useful in vitro system to study all aspects of cardiovascular function and disease, especially those related to mechanisms of hyperplasia and hypertrophy of intimal smooth muscle cells leading to vascular occlusion in atherosclerosis and stent restenosis.Characterization: positive for smooth muscle cell specific alpha-actin expression.
Other Notes
Basal Medium containing 10% FBS & 10% DMSO
Preparation Note
- 2nd passage, >500,000 cells in Basal Medium containing 10% FBS & 10% DMSO
- Can be cultured at least 10 doublings
Please refer to the HCtASMC Culture Protocol.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Till Seime et al.
Cells, 10(6) (2021-06-03)
Calcification is a prominent feature of late-stage atherosclerosis, but the mechanisms driving this process are unclear. Using a biobank of carotid endarterectomies, we recently showed that Proteoglycan 4 (PRG4) is a key molecular signature of calcified plaques, expressed in smooth
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