Skip to Content
Merck

A4562

5-(N,N-Dimethyl)amiloride hydrochloride

cAMP-dependent protein kinase inhibitor, powder

Synonym(s):

3-Amino-N-(aminoiminoethyl)-5-(dimethylamino)-6-chloropyrazinecarboxamide hydrochloride, DMA

Sign In to View Organizational & Contract Pricing.

Select a Size

All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C8H12ClN7O · HCl
CAS Number:
1214-79-5
Molecular Weight:
294.14
UNSPSC Code:
12352200
PubChem Substance ID:
24278216
NACRES:
NA.77
MDL number:
MFCD00069207

Product Name

5-(N,N-Dimethyl)amiloride hydrochloride,

SMILES string

Cl.CN(C)c1nc(N)c(nc1Cl)C(=O)\N=C(\N)N

InChI key

IIUPTHVVXMBJMQ-UHFFFAOYSA-N

InChI

1S/C8H12ClN7O.ClH/c1-16(2)6-4(9)13-3(5(10)14-6)7(17)15-8(11)12;/h1-2H3,(H2,10,14)(H4,11,12,15,17);1H

form

powder

storage temp.

2-8°C

Quality Level

200

Gene Information

human ... SCNN1A(6337), SCNN1B(6338), SCNN1D(6339), SCNN1G(6340), SLC9A1(6548)
mouse ... Scnn1a(20276), Scnn1b(20277), Scnn1d(140501), Scnn1g(20278)
rat ... Scnn1a(25122), Scnn1b(24767), Scnn1g(24768), Slc9a1(24782), Slc9a2(24783), Slc9a3(24784)

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

5-(N,N-Dimethyl)amiloride hydrochloride is a selective blocker of Na2/H+ antiport. 5-(N,N-Dimethyl)amiloride hydrochloride has been investigated for its ability to reduce inflammatory pain.

Biochem/physiol Actions

Selective blocker of Na+/H+ antiport; IC50 = 6.9 μM.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000299622
0000299621
0000299621
0000299622
0000259562

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Peter A Alpert et al.
Scientific reports, 7(1), 12693-12693 (2017-10-06)
Organic interfaces that exist at the sea surface microlayer or as surfactant coatings on cloud droplets are highly concentrated and chemically distinct from the underlying bulk or overlying gas phase. Therefore, they may be potentially unique locations for chemical or
D F Zhao et al.
Nature communications, 8, 14067-14067 (2017-02-22)
The terrestrial vegetation emits large amounts of volatile organic compounds (VOC) into the atmosphere, which on oxidation produce secondary organic aerosol (SOA). By acting as cloud condensation nuclei (CCN), SOA influences cloud formation and climate. In a warming climate, changes
Yered Pita-Juárez et al.
PLoS computational biology, 14(3), e1006042-e1006042 (2018-03-20)
A goal of genomics is to understand the relationships between biological processes. Pathways contribute to functional interplay within biological processes through complex but poorly understood interactions. However, limited functional references for global pathway relationships exist. Pathways from databases such as
Luca Bartolini et al.
Scientific reports, 8(1), 13697-13697 (2018-09-14)
Indentation is becoming increasingly popular to test soft tissues and (bio)materials. Each material exhibits an unknown intrinsic "mechanical behaviour". However, limited consensus on its "mechanical properties" (i.e. quantitative descriptors of mechanical behaviour) is generally present in the literature due to
Robert M Healy et al.
Analytical and bioanalytical chemistry, 407(20), 5899-5909 (2014-08-26)
Alkylamines are associated with both natural and anthropogenic sources and have been detected in ambient aerosol in a variety of environments. However, little is known about the ubiquity or relative abundance of these species in Europe. In this work, ambient
View All Related Papers

Related Content

Product Information Sheet - A4562

Product Information Sheet

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service