I2879
Inosine 5′-monophosphate from Saccharomyces cerevisiae
≥98%
Synonym(s):
I-5′-P, IMP, Inosinic Acid
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About This Item
Empirical Formula (Hill Notation):
C10H13N4O8P
CAS Number:
Molecular Weight:
348.21
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
205-045-1
MDL number:
Assay:
≥98%
Form:
powder
Solubility:
water: 100 mg/mL, clear to slightly hazy, colorless to almost colorless
Storage temp.:
−20°C
InChI key
GRSZFWQUAKGDAV-UHFFFAOYSA-N
InChI
1S/C10H13N4O8P/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20)
SMILES string
CC1(OCP(O)(O)=O)[C@@](O)(C)[C@@](C)(O)[C@@](N(C=N2)C3=C2C(NC=N3)=O)(C)O1
assay
≥98%
form
powder
solubility
water: 100 mg/mL, clear to slightly hazy, colorless to almost colorless
storage temp.
−20°C
Quality Level
Related Categories
Application
Inosine 5′-monophosphate (IMP) has been used as an umami tastant along with MSG to study their cortical responses and interactions in the human brain. It may be used as a substrate to study the distribution, specificity, and kinetics of inosine-5′-monophosphate dehydrogenase (IMPDH).
Biochem/physiol Actions
Inosine 5′-monophosphate is a purine nucleotide with a flavor-enhancing property. It acts as a precursor for the synthesis of both guanosine monophosphate (GMP) and adenosine monophosphate (AMP).
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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A novel process of inosine 5'-monophosphate production using overexpressed guanosine/inosine kinase.
H Mori et al.
Applied microbiology and biotechnology, 48(6), 693-698 (1998-02-11)
A novel process for producing inosine 5'-monophosphate (5'-IMP) has been demonstrated. The process consists of two sequential bioreactions; the first is a fermentation of inosine by a mutant of Corynebacterium ammoniagenes, and the second is a unique phosphorylating reaction of
Yasuka Toda et al.
The Journal of biological chemistry, 288(52), 36863-36877 (2013-11-12)
Umami taste perception in mammals is mediated by a heteromeric complex of two G-protein-coupled receptors, T1R1 and T1R3. T1R1/T1R3 exhibits species-dependent differences in ligand specificity; human T1R1/T1R3 specifically responds to L-Glu, whereas mouse T1R1/T1R3 responds more strongly to other L-amino
Haruhiko Oda et al.
Neurology, 81(20), 1741-1745 (2013-10-15)
To compare the usefulness of brain perfusion SPECT and (123)I-metaiodobenzylguanidine ((123)I-MIBG) in predicting the conversion of possible dementia with Lewy bodies (DLB) to probable DLB. We examined 94 patients with possible DLB based on the Consensus Criteria for the Clinical
Christine M Ordija et al.
American journal of physiology. Lung cellular and molecular physiology, 312(6), L1018-L1028 (2017-04-08)
Lung injury can release intracellular actin into the alveolar milieu and is also associated with increased susceptibility to secondary infections. We investigated the effect of free (extracellular) actin on lung macrophage host defense functions. Western blot analysis demonstrated free actin
Yuichi Yasutake et al.
Journal of gastroenterology and hepatology, 32(11), 1839-1845 (2017-03-16)
Uric acid is excreted from blood into the intestinal lumen, yet the roles of uric acid in intestinal diseases remain to be elucidated. The study aimed to determine whether uric acid could reduce end points associated with nonsteroidal anti-inflammatory drug
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