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About This Item
Linear Formula:
MgCl2
CAS Number:
Molecular Weight:
95.21
NACRES:
NA.52
PubChem Substance ID:
UNSPSC Code:
12352302
MDL number:
Grade:
Molecular Biology
Form:
liquid
Solubility:
water: soluble
grade
Molecular Biology
Quality Level
sterility
non-sterile; 0.2 μm filtered
form
liquid
concentration
1.00 M±0.01 M
technique(s)
DNA sequencing: suitable
impurities
DNAse, none detected, NICKase, none detected, Protease, none detected, RNAse, none detected
solubility
water: soluble
density
1.080 g/cm3
cation traces
heavy metals (as Pb): ≤5 ppm
suitability
suitable for electrophoresis, suitable for molecular biology
application(s)
cell analysis
foreign activity
DNase, RNase, NICKase and protease, none detected
SMILES string
Cl[Mg]Cl
InChI
1S/2ClH.Mg/h2*1H;/q;;+2/p-2
InChI key
TWRXJAOTZQYOKJ-UHFFFAOYSA-L
General description
Magnesium chloride is a common ionic halide that readily dissolves in water. It plays various crucial biological roles in enzymology, cell membrane/wall structure, muscle cell physiology, and nucleic acid composition. Additionally, magnesium chloride serves as an essential co-factor in numerous enzymes, including DNAse, specific restriction enzymes, and Ribonuclease H. It is widely utilized to provide magnesium ions in diverse molecular biology applications, including PCR reactions.
Application
Magnesium chloride is widely used to supply the magnesium ion in various molecular biology applications, including PCR reactions and buffers. It has been used -
- to prepare buffer to lyse cells for immunoprecipitation
- as a supplement in Krebs-Henseleit buffer in chronic high-fat diet studies of aged mice.
- in embedding 3-dimensional mtgase hydrogels in invitro studies of osteocyte differentitaion and interconnected cellular networks.
- It has been used to protect the liver from oxidative damage.
- to prepare serum-free medium for electrophysiological studies of rat brain slice cultures.
Features and Benefits
- Available as a Ready-to-use solution which reduces the need for preparation time.
- Heavy metals (as Pb): ≤5 ppm
- Free from DNase, RNase, NICKase and protease
Other Notes
For additional information on our range of Biochemicals, please complete this form.
Magnesium chloride solution contains 1M magnesium chloride in 18 megaohm water.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
ppe
Eyeshields, Gloves
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Related Content
Product Information Sheet
Protective Effects of Magnesium Chloride on Liver Enzymes and Biomarkers of Oxidative Stress in high fat diet fed Rats
Mohammed et, al
Nigerian Journal of Physiological Sciences : Official Publication of the Physiological Society of Nigeria, 34(2), 149-157 (2019)
M J Mc Garrigle et al.
European cells & materials, 31, 323-340 (2016-05-25)
Extracellular matrix (ECM) stiffness and cell density can regulate osteoblast differentiation in two dimensional environments. However, it is not yet known how osteoblast-osteocyte differentiation is regulated within a 3D ECM environment, akin to that existing in vivo. In this study
Yelena Y Grinberg et al.
Journal of neurochemistry, 122(1), 221-229 (2012-04-25)
Spreading depression (SD), the likely cause of migraine aura and perhaps migraine, is triggered by widespread and unfettered neuronal hyperexcitability. Migraine and the initiating hyperexcitability of seizure, which involve oxidative stress (OS), are likely interrelated. Environmental enrichment (EE) decreases seizure