M4139
S-Methylglutathione
>98% (TLC), suitable for cell culture
Synonym(s):
L-γ-glutamyl-S-methyl-L-cysteinyl-glycine
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About This Item
Empirical Formula (Hill Notation):
C11H19N3O6S
CAS Number:
Molecular Weight:
321.35
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
MDL number:
Product Name
S-Methylglutathione,
assay
>98% (TLC)
Quality Level
form
powder
technique(s)
cell culture | mammalian: suitable
color
white
storage temp.
2-8°C
SMILES string
CSCC(NC(=O)CCC(N)C(O)=O)C(=O)NCC(O)=O
InChI
1S/C11H19N3O6S/c1-21-5-7(10(18)13-4-9(16)17)14-8(15)3-2-6(12)11(19)20/h6-7H,2-5,12H2,1H3,(H,13,18)(H,14,15)(H,16,17)(H,19,20)
InChI key
QTQDDTSVRVWHMO-UHFFFAOYSA-N
General description
Useful as a glyoxylase inhibitor.
Biochem/physiol Actions
S-methylglutathione is a methionine containing peptide and glyoxylase inhibitor.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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C Sherrill et al.
Journal of bacteriology, 180(6), 1454-1459 (1998-03-27)
Glutathione (gamma-GluCysGly, GSH) is not found in most gram-positive bacteria, but some appear to synthesize it and others, including Streptococcus mutans ATCC 33402, import it from their growth medium. Import of oxidized glutathione (GSSG) by S. mutans 33402 in 7H9
Alice Rothnie et al.
Molecular pharmacology, 74(6), 1630-1640 (2008-09-05)
Multidrug resistance protein 1 (MRP1/ABCC1) is an ATP-dependent polytopic membrane protein that transports many anticancer drugs and organic anions. Its transport mechanism is multifaceted, especially with respect to the participation of GSH. For example, vincristine is cotransported with GSH, estrone
K Ohta et al.
Biochimica et biophysica acta, 1117(2), 136-142 (1992-09-15)
Hydra shows at least 5 components of the behavioral response (R1-R5) which are evoked at different concentrations of S-methylglutathione (GSM). We have prepared several monoclonal antibodies (mAbs), each of which depressed specific responses and visualized specific structures. In this paper