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Merck

P5884

Brij® 58

average Mn ~1124

Synonym(s):

Polyethylene glycol hexadecyl ether, Polyoxyethylene (20) cetyl ether

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About This Item

Linear Formula:
HO(CH2CH2O)20C16H33
CAS Number:
9004-95-9
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
24898715
MDL number:
MFCD00080892
Beilstein/REAXYS Number:
1899885

Product Name

Brij® 58, average Mn ~1124

InChI

1S/C56H114O21/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17-58-19-21-60-23-25-62-27-29-64-31-33-66-35-37-68-39-41-70-43-45-72-47-49-74-51-53-76-55-56-77-54-52-75-50-48-73-46-44-71-42-40-69-38-36-67-34-32-65-30-28-63-26-24-61-22-20-59-18-16-57/h57H,2-56H2,1H3

SMILES string

CCCCCCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI key

NLMKTBGFQGKQEV-UHFFFAOYSA-N

description

non-ionic

form

solid

mol wt

micellar avg mol wt 79,000
average Mn ~1124

aggregation number

70

technique(s)

protein quantification: suitable

CMC

0.08 mM (20-25°C)

mp

~38 °C

transition temp

cloud point >100 °C

HLB

16

Quality Level

200

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Application

Polyethylene glycol hexadecyl ether, or Brij 58, has been used in a study to assess properties of gemini-conventional surfactant mixtures and their effects on solubilization of polycyclic aromatic hydrocarbons. It has also been used in a study to investigate RNase-sensitive constraint of bacterial nucleoid structure.

General description

Brij 58 is a nonionic surfactant or detergent for protein extraction and permeabilization of cells. It may be used in the preparation of yeast spheroplasts.

Legal Information

Brij is a registered trademark of Croda International PLC

pictograms

Environment
GHS09

hcodes

H411

Hazard Classifications

Aquatic Chronic 2

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

302.0 °F - closed cup

flash_point_c

150 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000512997
0000512616
0000512997
0000512616
0000501806

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Macromolecular crowding can account for RNase-sensitive constraint of bacterial nucleoid structure
Foley, P., et al
Biochemical and Biophysical Research Communications, 395, 6-6 (2010)
Study of surface and solution properties of gemini-conventional surfactant mixtures and their effects on solubilization of polycyclic aromatic hydrocarbons
Panda
Journal of Molecular Liquids, 163, 6-6 (2011)
Photodestruction of BDE-99 in micellar solutions of nonionic surfactants of Brij 35 and Brij 58
Li, X., et al.
Chemosphere, 78, 8-8 (2010)
M Kellermayer et al.
Journal of cellular physiology, 159(2), 197-204 (1994-05-01)
The plasma membrane of erythrocytes, as of other cells, is thought to act as the barrier responsible for maintaining intracellular gradients of most ions and small molecular species between the cell and its environment. Controlled application of the nonionic detergent
Preparation of extracts from prokaryotes.
M Cull et al.
Methods in enzymology, 182, 147-153 (1990-01-01)
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Product Information Sheet - P5884

Product Information Sheet

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