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Merck

CRM48665

Benzo[a]pyrene solution

certified reference material, TraceCERT®, 200 μg/mL in methylene chloride

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About This Item

Empirical Formula (Hill Notation):
C20H12
CAS Number:
50-32-8
Molecular Weight:
252.31
NACRES:
NA.24
PubChem Substance ID:
329798456
UNSPSC Code:
41116107
MDL number:
MFCD00003602

Key Documents

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InChI

1S/C20H12/c1-2-7-17-15(4-1)12-16-9-8-13-5-3-6-14-10-11-18(17)20(16)19(13)14/h1-12H

SMILES string

c1ccc2c(c1)cc3ccc4cccc5ccc2c3c45

InChI key

FMMWHPNWAFZXNH-UHFFFAOYSA-N

grade

certified reference material, TraceCERT®

product line

TraceCERT®

CofA

current certificate can be downloaded

feature

standard type calibration

packaging

ampule of 1 mL

concentration

200 μg/mL in methylene chloride

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

Quality Level

300

application(s)

environmental

format

single component solution

storage temp.

2-30°C

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General description

This compound is listed in the SVHC (Substances of very high concern) candidate list of ECHA (European Chemicals Agency)

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Aquatic Chronic 3 - Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

75-09-2 + 50-32-8

CAS No.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Gunnar Boysen et al.
Mutation research, 543(1), 17-30 (2003-01-03)
We review studies which investigate the presence, using structure-specific analytical methods, of DNA or protein adducts of the carcinogen benzo[a]pyrene (BaP) in human tissues. The analytical methods include high performance liquid chromatography with fluorescence detection and gas chromatography-mass spectrometry. Although
Luchun Duan et al.
Environment international, 70, 192-202 (2014-06-18)
Oral bioavailability of benzo[a]pyrene (B[a]P) was studied in a swine model using eight spiked soil samples after incubation for 50 and/or 90 days. Silica sand was used as a reference material and the relative bioavailability (RB) of B[a]P in soils
K P Miller et al.
Drug metabolism reviews, 33(1), 1-35 (2001-03-29)
Polycyclic aromatic hydrocarbons are ubiquitous contaminants in the environment. Benzo[a]pyrene (BaP), a prototypical member of this class of chemicals, has been extensively studied for its toxic effects in laboratory animals and human populations. BaP toxicity is often mediated by oxidative
Studies on the metabolism of benzo[a]pyrene and dose-dependent differences in the mutagenic profile of its ultimate carcinogenic metabolite.
A H Conney et al.
Drug metabolism reviews, 26(1-2), 125-163 (1994-01-01)
F Mermillod-Blondin et al.
The Science of the total environment, 450-451, 230-241 (2013-03-19)
The interactions between invertebrates and micro-organisms living in streambed sediments often play key roles in the regulation of nutrient and organic matter fluxes in aquatic ecosystems. However, benthic sediments also constitute a privileged compartment for the accumulation of persistent organic
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