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Merck

1031503

USP

Amoxicillin

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Amoxicillin trihydrate

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About This Item

Empirical Formula (Hill Notation):
C16H19N3O5S · 3H2O
CAS Number:
Molecular Weight:
419.45
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
7507120

Product Name

Amoxicillin, United States Pharmacopeia (USP) Reference Standard

InChI key

MQXQVCLAUDMCEF-CWLIKTDRSA-N

SMILES string

O.O.O.CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(O)=O

InChI

1S/C16H19N3O5S.3H2O/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7;;;/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24);3*1H2/t9-,10-,11+,14-;;;/m1.../s1

grade

pharmaceutical primary standard

API family

amoxicillin

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

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Application

Amoxicillin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Amoxicillin Tablets
  • Amoxicillin Capsules
  • Amoxicillin Boluses
  • Amoxicillin Oral Suspension
  • Amoxicillin Intramammary Infusion
  • Amoxicillin for Injectable Suspension

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Certificates of Analysis (COA)

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Amoxicillin Capsules
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(6), 300-300 (2013)
Amoxicillin Boluses
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 299-299 (2013)
Amoxicillin Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(6), 304-304 (2021)
Amoxicillin
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(3), 297-297 (2020)
Tony Antoniou et al.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 187(4), E138-E143 (2015-02-04)
Trimethoprim-sulfamethoxazole increases the risk of hyperkalemia when used with spironolactone. We examined whether this drug combination is associated with an increased risk of sudden death, a consequence of severe hyperkalemia. We conducted a population-based nested case-control study involving Ontario residents

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