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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
polyclonal
Species reactivity:
human, rat, pig, mouse
Application:
IP, WB
Citations:
8
Product Name
Anti-Integrin β1 Antibody, cytosolic, Chemicon®, from rabbit
biological source
rabbit
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, rat, pig, mouse
manufacturer/tradename
Chemicon®
technique(s)
immunoprecipitation (IP): suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... ITGB1(3688)
General description
130kDa
Immunogen
Epitope: cytosolic
Synthetic peptide corresponding to the C-terminus of human integrin beta 1 (a.a. CTTVVNPKYEGK)
Application
Detect Integrin β1 using this Anti-Integrin β1 Antibody, cytosolic validated for use in IP & WB.
Western blot: 1-2μg/mL for detection in whole cell lysate. The antibody is effective against reduced (MW = 130kDa) and non-reduced (MW = 110kDa) proteins.
Immunoprecipitation
Optimal working dilutions must be determined by the end user.
Immunoprecipitation
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Reactive with human, mouse, and rat integrin beta-1, as confirmed by western blot. Not reactive with other integrins.
Physical form
Format: Purified
Protein A Purified immunoglobulin. Liquid in PBS containing 0.1% sodium azide.
Analysis Note
Control
U251 cell line Skin (Basement Membrane)
U251 cell line Skin (Basement Membrane)
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Jean-Baptiste Oudart et al.
Cell adhesion & migration, 15(1), 215-223 (2021-07-27)
We previously demonstrated that F4 peptide (CNPEDCLYPVSHAHQR) from collagen XIX was able to inhibit melanoma cell migrationin vitro and cancer progression in a mouse melanoma model. The aim of the present work was to study the anti-angiogenic properties of F4 peptide. We demonstrated that F4
Xiaoming Bai et al.
Scientific reports, 4, 6538-6538 (2014-10-08)
Prostaglandin E2 (PGE2) has been implicated in cell invasion in hepatocellular carcinoma (HCC), via increased β1-integrin expression and cell migration; however, the mechanism remains unclear. PGE2 exerts its effects via four subtypes of the E prostanoid receptor (EP receptor 1-4).
Alexia Vautrin-Glabik et al.
Frontiers in cell and developmental biology, 8, 775-775 (2020-08-28)
Angiogenesis is defined as the formation of new capillaries by sprouting from the pre-existing microvasculature. It occurs in physiological and pathological processes particularly in tumor growth and metastasis. α1, α2, α3, and α6 NC1 domains from type IV collagen were
Global Trade Item Number
| SKU | GTIN |
|---|---|
| AB1952P | 04053252621383 |