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About This Item
CAS Number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25
MDL number:
SMILES string
[*]OC[C@H]1O[C@@H](O[C@@H]2[C@@H](CO[*])O[C@@H](O[*])[C@H](O[*])[C@H]2O[*])[C@H](O[*])[C@@H](O[*])[C@@H]1O[*]
InChI key
YLGXILFCIXHCMC-JHGZEJCSSA-N
form
powder
color
white to off-white
viscosity
20-30 cP, 2 % in water(20 °C)
Quality Level
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General description
Methyl cellulose (MC) is a simple derivative of cellulose.
Application
Methyl cellulose has been used:
- as a supplement for culturing multicellular spheroids of SH-SY5Y cells
- as a supplement for culturing tumor cell spheroids
- to generate and study the rheological behavior of aqueous mullite-albumin-methylcellulose systems
Biochem/physiol Actions
Methyl cellulose (MC) acts as a laxative and is hydrophilic. It has therapeutic effects against constipation, irritable bowel syndrome, and diverticulosis due to its bulk-forming and stool softening properties. MC has the potential to treat patients with ileostomies and colostomies. It may also be used as a stabilizer and emulsifier. MC is a component of eye drops and contact lens solutions.
Other Notes
To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Dirk van den Brand et al.
Biochimica et biophysica acta, 1860(6), 1342-1349 (2018-03-20)
Drug delivery into tumors and metastases is a major challenge in the eradication of cancers such as epithelial ovarian carcinoma. Cationic cell-penetrating peptides (CPPs) are a promising group of delivery vehicles to mediate cellular entry of molecules that otherwise poorly
Rheological behavior of aqueous mullite-albumin-methylcellulose systems
Sandoval M, et al.
Ceramics International, 43(9) (2017)
Eyedrops and ointments
Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions, 220-221 (2016)
Methylcellulose, a cellulose derivative with original physical properties and extended applications
Nasatto P L, et al.
Polymers, 7(5), 777-803 (2015)
Timo Z Nazari-Shafti et al.
Biomolecules, 10(9) (2020-09-26)
The cardioprotective properties of extracellular vesicles (EVs) derived from mesenchymal stromal cells (MSCs) are currently being investigated in preclinical studies. Although microRNAs (miRNAs) encapsulated in EVs have been identified as one component responsible for the cardioprotective effect of MSCs, their
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