A3882
Alizarin-3-methyliminodiacetic acid
≥98% (TLC), powder
Synonym(s):
N-(carboxymethyl)-N-[(9,10-dihydro-3,4-dihydroxy-9,10-dioxo-2-anthracenyl)methyl]-glycine, 3,4-Dihydroxyanthraquinon-2-yl-methylimino-diacetic acid, Alizarin Complexone, Alizarin Fluorine Blue
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About This Item
Empirical Formula (Hill Notation):
C19H15NO8
CAS Number:
Molecular Weight:
385.32
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
223-544-2
MDL number:
Beilstein/REAXYS Number:
2190028
Product Name
Alizarin-3-methyliminodiacetic acid,
assay
≥98% (TLC)
Quality Level
form
powder
solubility
1 M NaOH: 10 mg/mL, blue to purple
SMILES string
OC(=O)CN(CC(O)=O)Cc1cc2C(=O)c3ccccc3C(=O)c2c(O)c1O
InChI
1S/C19H15NO8/c21-13(22)7-20(8-14(23)24)6-9-5-12-15(19(28)16(9)25)18(27)11-4-2-1-3-10(11)17(12)26/h1-5,25,28H,6-8H2,(H,21,22)(H,23,24)
InChI key
PWIGYBONXWGOQE-UHFFFAOYSA-N
General description
Alizarin-3-methyliminodiacetic acid is used in the colorimetric detection of fluorine. It is a dye employed to stain mineralized bones of the preserved specimen from vertebrates.
Application
Alizarin-3-methyliminodiacetic acid has been used:
- for live staining of mineralized bone matrix
- to double-label the bone for dynamic bone histomorphometry at the femoral mid-diaphysis in the rat
- as a label in histomorphometry of the tibial diaphysis to indicate new bone formation in the rat
Legal Information
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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E Edelmann et al.
Advances in space research : the official journal of the Committee on Space Research (COSPAR), 33(8), 1390-1394 (2005-04-05)
Previous investigations on neonate swordtail fish (Xiphophorus helleri) revealed that otolithic calcium incorporation (visualized using the calcium tracer alizarin complexone) and thus otolith growth had ceased after nerve transection, supporting a hypothesis according to which the gravity-dependent otolith growth is
Ling Zhu et al.
Dalton transactions (Cambridge, England : 2003), 48(15), 5035-5047 (2019-03-28)
A complexone analog chemosensor, H2L, bearing chelating bis(2-pyridylmethyl) amine and alizarin groups was synthesized via the Mannich reaction. H2L chromically responds to OH-, F-, CH3COO-, and H2PO4- in DMF, CH3CN, and acetone, but not in CH3OH or H2O. The addition
Bi Foua Claude Alain Gohi et al.
Cell & bioscience, 10, 2-2 (2020-01-11)
A two-stage method of obtaining viable human amniotic stem cells (hAMSCs) in large-scale is described. First, human amniotic stem cells are isolated via dual enzyme (collagenase II and DNAase I) digestion. Next, relying on a culture of the cells from