SML2602
CW3388
≥98% (HPLC)
Synonym(s):
1-([1,1′-Biphenyl]-4-ylmethyl)octahydro-azocine
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About This Item
Empirical Formula (Hill Notation):
C20H25N
CAS Number:
Molecular Weight:
279.42
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
oil
assay
≥98% (HPLC)
form
oil
color
colorless to yellow
storage temp.
2-8°C
SMILES string
N3(CCCCCCC3)Cc1ccc(cc1)c2ccccc2
InChI
1S/C20H25N/c1-2-7-15-21(16-8-3-1)17-18-11-13-20(14-12-18)19-9-5-4-6-10-19/h4-6,9-14H,1-3,7-8,15-17H2
InChI key
BTDKOFMWYIXWST-UHFFFAOYSA-N
Biochem/physiol Actions
CW3388 is a cell active and highly potent enhancer of oligodendrocyte formation. CW3388 potently inhibits the cholesterol biosynthesis enzyme Δ8,7-sterol isomerase (EBP). It promotes myelination in vitro.
cell active and highly potent enhancer of oligodendrocyte formation; inhibitor of Δ8,7-sterol isomerase (EBP)
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Dharmaraja Allimuthu et al.
Cell chemical biology, 26(4), 593-599 (2019-02-19)
Small molecules that promote oligodendrocyte formation have been identified in "drug repurposing" screens to nominate candidate therapeutics for diseases in which myelin is lost, including multiple sclerosis. We recently reported that many such molecules enhance oligodendrocyte formation not by their