T8691
Taurine
suitable for cell culture, BioXtra, meets USP testing specifications
Synonym(s):
2-Aminoethanesulfonic acid
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About This Item
Linear Formula:
NH2CH2CH2SO3H
CAS Number:
Molecular Weight:
125.15
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
203-483-8
MDL number:
Beilstein/REAXYS Number:
1751215
Product Name
Taurine, suitable for cell culture, meets USP testing specifications
agency
meets USP testing specifications
Quality Level
product line
BioXtra
form
crystalline powder
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
color
white
mp
>300 °C (lit.)
SMILES string
NCCS(O)(=O)=O
InChI
1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)
InChI key
XOAAWQZATWQOTB-UHFFFAOYSA-N
Gene Information
rat ... Ppm1a(24666)
Application
Taurine has been used:
- as a component of cardiomyocyte dissociation solution
- as a supplement for modified synthetic oviduct fluid (m-SOF) medium to culture the presumptive zygotes
- as a constituent of low Ca2+ solution employed in preparation of collagenase B solution for colony dissociation into single cells
- to assess its effect on development of bovine embryos fertilized with different bull semen during in vitro fertilization
- as a component of culture media for derivation of cornea organoids
Biochem/physiol Actions
Taurine is predominantly found in the retina and heart and is also found in the brain, intestine, skeletal muscles and kidneys. It controls the concentration of intracellular calcium, protects against ischemia-reperfusion injury and possesses blood pressure-lowering properties. Taurine also plays a vital role in bile formation and fat digestion. Deficiency of taurine is associated with development of anxiety, hyperactivity, epilepsy and depression.
Non-selective endogenous agonist at glycine receptors.
Non-selective endogenous agonist at glycine receptors. Conditionally essential sulfonated amino acid which modulates apoptosis in some cells; functions in many metabolic activities; a product of methionine and cysteine metabolism.
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Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Patient-specific induced pluripotent stem cell models: generation and characterization of cardiac cells
Zanella F and Sheikh F
Methods in Molecular Biology, 147-162 (2014)
The Effect of Various Concentrations of Taurine during In vitro Fertilization on the Development of Bovine Embryos Fertilized with Spermatozoa from Three Different Bulls
Tsuzuki Y, et al.
Asian-Australasian Journal of Animal Sciences (2010)
Scalable expansion of human pluripotent stem cells in suspension culture
Zweigerdt R, et al.
Nature Protocols, 6(5), 689-689 (2011)