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Merck

412201

L-Serine methyl ester hydrochloride

98%, for peptide synthesis

Synonym(s):

L-Serine methyl ester·HCl

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About This Item

Linear Formula:
HOCH2CH(NH2)COOCH3 · HCl
CAS Number:
Molecular Weight:
155.58
NACRES:
NA.22
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
227-140-7
MDL number:
Beilstein/REAXYS Number:
3559591
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Product Name

L-Serine methyl ester hydrochloride, 98%

Quality Level

assay

98%

form

powder

optical activity

[α]20/D +3.4°, c = 4 in methanol

reaction suitability

reaction type: solution phase peptide synthesis

mp

163 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

Cl.COC(=O)[C@@H](N)CO

InChI

1S/C4H9NO3.ClH/c1-8-4(7)3(5)2-6;/h3,6H,2,5H2,1H3;1H/t3-;/m0./s1

InChI key

NDBQJIBNNUJNHA-DFWYDOINSA-N



Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Carlos Aydillo et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 13(17), 4840-4848 (2007-03-17)
A new chiral serine equivalent and its enantiomer have been synthesized from (S)- and (R)-N-Boc-serine methyl esters (Boc: tert-butyloxycarbonyl). The use of these compounds as chiral building blocks has been demonstrated in the synthesis of alpha-alkyl alpha-amino acids by diastereoselective
Yu Harayama et al.
Chemical communications (Cambridge, England), (13)(13), 1764-1766 (2005-03-26)
The use of hypervalent iodine(III) reagents allowed us to develop the novel and efficient direct synthesis of N,O-acetal compounds via the oxidative fragmentation reaction of alpha-amino acids or alpha-amino alcohols; furthermore, we succeeded in developing an improved synthesis of the
Ernest Mordret et al.
Molecular cell, 75(3), 427-441 (2019-07-30)
The translation machinery and the genes it decodes co-evolved to achieve production throughput and accuracy. Nonetheless, translation errors are frequent, and they affect physiology and protein evolution. Mapping translation errors in proteomes and understanding their causes is hindered by lack