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Merck

499552

Zinc preparation

5 g/dL Zn2+ in THF, highly reactive Rieke®metal

Synonym(s):

Zn

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About This Item

Linear Formula:
Zn
CAS Number:
Molecular Weight:
65.39
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12161600
MDL number:
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Quality Level

reaction suitability

core: zinc, reagent type: catalyst

concentration

5 g/dL Zn2+ in THF

density

0.949 g/mL at 25 °C

storage temp.

2-8°C

SMILES string

[Zn]

InChI

1S/Zn

InChI key

HCHKCACWOHOZIP-UHFFFAOYSA-N

Application

Rieke® Zinc metal can be used to reduce common organic functional groups such as aromatic nitro, conjugated aldehydes, arylacetylenes, and phenylpropiolates.

Legal Information

Product of Rieke Metals, Inc.
Rieke is a registered trademark of Rieke Metals, Inc.
Rieke is a registered trademark of Rieke Metals, Inc.


signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Central nervous system, Respiratory system

supp_hazards

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

1.0 °F - closed cup

flash_point_c

-17.22 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter



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Rieke zinc as a reducing agent for common organic functional groups
Kroemer J, et al.
Tetrahedron Letters, 47(36), 6339-6341 (2006)
Casper Groth et al.
Development (Cambridge, England), 140(14), 3018-3027 (2013-06-21)
Developmental patterning requires the precise interplay of numerous intercellular signaling pathways to ensure that cells are properly specified during tissue formation and organogenesis. The spatiotemporal function of the Notch signaling pathway is strongly influenced by the biosynthesis and intracellular trafficking
I A Popov et al.
Molekuliarnaia biologiia, 47(3), 498-504 (2013-07-31)
Alzheimer's disease, is a lethal neurodegenerative pathology, characterized by the formation of soluble neurotoxic oligomers of the human amyloid-beta peptide Abeta which get accumulated forming polymeric extracellular aggregates (so-called amyloid plaques). The isomerized at aspartate 7 isoform of the human