Skip to Content
Merck

Key Documents

View All Documentation

P8074

TWEEN® 80

BioXtra, viscous liquid

Synonym(s):

TWEEN® 80, POE (20) sorbitan monooleate, Polyethylene glycol sorbitan monooleate, Polyoxyethylenesorbitan monooleate, Polysorbate 80

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

CAS Number:
9005-65-6
UNSPSC Code:
12161900
NACRES:
NA.21
MDL number:
MFCD00082107
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

description

non-ionic

Quality Segment

200

product line

BioXtra

form

viscous liquid

mol wt

micellar avg mol wt 79,000, average mol wt 1310

composition

Oleic acid, ~70% (balance primarily linoleic, palmitic, and stearic acids)

aggregation number

60

technique(s)

DNA extraction: suitable, RNA extraction: suitable, cell culture | mammalian: suitable, protein purification: suitable

impurities

≤0.025% Phosphorus (P)

ign. residue

<0.1%

CMC

0.012 mM (20-25°C)

transition temp

cloud point 65 °C

density

1.06 g/mL at 25 °C

anion traces

chloride (Cl-): <0.05%, sulfate (SO42-): <0.05%

cation traces

Al: <0.0005%, Ca: <0.001%, Cu: <0.0005%, Fe: <0.0005%, K: <0.005%, Mg: <0.0005%, NH4+: <0.05%, Na: <0.05%, Pb: <0.001%, Zn: <0.0005%

HLB

15

SMILES string

CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO

InChI

1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+

InChI key

RGPBUVUVZKQNHD-MDZDMXLPSA-N

General description

["TWEEN"] 80 is a polyethylene sorbitol ester, broadly used in biochemical applications like solubilizing proteins, isolating nuclei from cells in culture, and growing tubercle bacilli. It is also useful in emulsifying and dispersing substances in medicinal and food products. TWEEN 80 acts as an active drying agent in ice cream.

Application

["TWEEN"] 80 has been used:
  • to dissolve rapamycin (RAPA) for immunosuppressive treatment to perform in vivo studies in mice
  • to dissolve remodelin and remodelin Fluor to assess remodelin toxicity in vivo and small molecule dosing
  • to prepare assay medium for the microbiological assay for total folate

Legal Information

TWEEN is a registered trademark of Croda International PLC

Still not finding the right product?

Explore all of our products under TWEEN® 80

Storage Class

10 - Combustible liquids

ppe

Eyeshields, Gloves

flash_point_f

>482.0 °F - Cleveland open cup

flash_point_c

> 250 °C - Cleveland open cup

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library