H6501
DL-β-Hydroxybutyric acid sodium salt
~98%, powder
Synonym(s):
(±)-3-Hydroxybutanoic acid sodium salt
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About This Item
Linear Formula:
C4H7O3Na
CAS Number:
Molecular Weight:
126.09
NACRES:
NA.83
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
205-774-5
MDL number:
Product Name
DL-β-Hydroxybutyric acid sodium salt, ~98%
assay
~98%
Quality Segment
form
powder
solubility
water: 1 g/10 mL, clear, colorless
storage temp.
2-8°C
SMILES string
[Na].CC(O)CC(O)=O
InChI
1S/C4H8O3.Na/c1-3(5)2-4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1
InChI key
NBPUSGBJDWCHKC-UHFFFAOYSA-M
Application
DL-β-Hydroxybutyric acid sodium salt has been used:
- as a standard for quantifying blood plasma and milk β-hydroxybutyric acid in Danish Jersey cows
- to investigate its anticonvulsant effects in epilepsy induced rats
- to induce hyperketonemia in Holstein dairy cows
Biochem/physiol Actions
β-Hydroxybutyric acid is a ketone body present in the rumen epithelium of liver cells. Its interconversion to acetoacetate influences the acid-base balance and is coupled NADH generation from (nicotinamide adenine dinucleotide) NAD+, measured fluorimetrically. A high plasma level of β-hydroxybutyric acid is implicated in diabetic ketoacidosis. It traverses the blood-brain barrier as a monocarboxylic acid. β-Hydroxybutyric acid may play a protective role in dopaminergic neurodegeneration in Parkinson′s disease model. β-Hydroxybutyric acid is a ligand for G protein-coupled receptor(GPR109A) and favors inhibition of secretion, transcription and translation of growth hormone (GH) and prolactin (PRL) gene in cow anterior pituitary cells (DCAPCs).
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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