P0381
Pyrogallol
≥98% (HPLC)
Synonym(s):
1,2,3-Trihydroxybenzene, 2,3-Dihydroxyphenol, Pyrogallic acid
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About This Item
Linear Formula:
C6H3(OH)3
CAS Number:
Molecular Weight:
126.11
UNSPSC Code:
12191503
NACRES:
NA.21
PubChem Substance ID:
EC Number:
201-762-9
Beilstein/REAXYS Number:
907431
MDL number:
Assay:
≥98% (HPLC)
Grade:
HPLC grade
Technique(s):
HPLC: suitable
Bp:
309 °C (lit.)
Vapor pressure:
10 mmHg ( 167.7 °C)
grade
HPLC grade
Quality Level
vapor density
4.4 (vs air)
vapor pressure
10 mmHg ( 167.7 °C)
assay
≥98% (HPLC)
form
powder
technique(s)
HPLC: suitable
pH
5.8 (10 g/L)
bp
309 °C (lit.)
mp
133-134 °C (lit.)
solubility
ethanol: 50 mg/mL, clear, colorless
application(s)
cell analysis
SMILES string
Oc1cccc(O)c1O
InChI
1S/C6H6O3/c7-4-2-1-3-5(8)6(4)9/h1-3,7-9H
InChI key
WQGWDDDVZFFDIG-UHFFFAOYSA-N
General description
Pyrogallol is a polyphenol and allelochemical, found on Microcystis aeruginosa and Emblica officinalis.
Application
Pyrogallol has been used:
- in the superoxide dismutase (SOD) assay
- to induce modification in mitochondrial DNA and to characterize the same
- as a standard to confirm the presence of pyrogallol in butanol fraction of white rose petal extract
Biochem/physiol Actions
Pyrogallol induces superoxide anion (O2-) generation and in the presence of metal ions, it stimulates oxidative damage to DNA and lipids.
Analysis Note
May contain black specks.
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signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Muta. 2
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Effect of oxaliplatin combined with polyenephosphatidylcholine on the proliferation of human gastric cancer SGC-7901 cells
Jiang T, et al.
Oncology Letters, 12(6), 4538-4546 (2016)
Neuroprotective effects of a butanol fraction of Rosa hybrida petals in a middle cerebral artery occlusion model
Yang G, et al.
Biomolecules & Therapeutics, 21(6), 454-454 (2013)
Mitochondrial DNA acquires immunogenicity on exposure to nitrosative stress in patients with vitiligo
Al-Shobaili HA and Rasheed Z
Human immunology, 75(10), 1053-1061 (2014)