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195596

sec-Butyllithium solution

1.4 M in cyclohexane

Synonym(s):

Lithium-2-butanide, s-BuLi

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About This Item

Linear Formula:
CH3CH2CH(CH3)Li
CAS Number:
598-30-1
Molecular Weight:
64.06
UNSPSC Code:
12352103
NACRES:
NA.22
PubChem Substance ID:
24851700
MDL number:
MFCD00009323
Beilstein/REAXYS Number:
3587206
Concentration:
1.4 M in cyclohexane
Form:
liquid
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form

liquid

Quality Level

200

concentration

1.4 M in cyclohexane

density

0.769 g/mL at 25 °C

storage temp.

2-8°C

SMILES string

[Li]C(C)CC

InChI

1S/C4H9.Li/c1-3-4-2;/h3H,4H2,1-2H3;

InChI key

VATDYQWILMGLEW-UHFFFAOYSA-N

Application

sec-Butyllithium solution (1.4M in cyclohexane) has been used in the multi-step synthesis of 5-methyl-5,6-dihydrothymidine (5-MDHT) from thymidine. It has also been used in the copper-catalyzed asymmetric allylic alkylation (AAA) of allyl bromides, chlorides, and ethers in the presence of a chiral ligand.

Packaging

The 25 mL Sure/Seal™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

Legal Information

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

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Danger

target_organs

Central nervous system

Storage Class

4.2 - Pyrophoric and self-heating hazardous materials

wgk

WGK 2

flash_point_f

1.4 °F - closed cup

flash_point_c

-17 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Eye Dam. 1 - Flam. Liq. 2 - Pyr. Liq. 1 - Skin Corr. 1B - STOT SE 3 - Water-react. 1

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Certificates of Analysis (COA)

Lot/Batch Number
SDBB8543
SHBT4322
SDBB2942
SHBS7881
SHBS3401

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Articles

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