MILLIPLEX^® Rat Vascular Injury Panel

Biomarkers such as Caveolin-1, CTGF, KC/GRO (CXCL1), IL-6, MCP-1 (CCL2), PAI-1 (Total), TIMP-1, TNFα, and VEGF are central to understanding vascular injury, inflammation, and tissue remodeling in rat models. Caveolin-1 regulates endothelial function and vascular permeability, while CTGF is involved in fibrosis and extracellular matrix production. KC/GRO and MCP-1 are chemokines that mediate immune cell recruitment. IL-6 and TNFα are pro-inflammatory cytokines linked to vascular inflammation. PAI-1 and TIMP-1 regulate fibrinolysis and matrix turnover, and VEGF promotes angiogenesis. Together, these analytes provide a comprehensive profile of vascular damage, repair, and inflammatory signaling

MILLIPLEX^® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 9 analytes in rat serum or plasma samples.

Analytes included: Caveolin-1, CTGF, KC/GRO (CXCL1), IL-6, MCP-1 (CCL2), PAI-1 (Total), TIMP-1, TNFα, VEGF

Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Features:

• Targets a broad panel of biomarkers involved in vascular injury, inflammation, and tissue remodeling
• Includes 9 analytes covering endothelial function, chemokine signaling, cytokine activity, and angiogenesis
• Multiplex format enables simultaneous detection from minimal sample volume
• Compatible with rat serum, plasma, and tissue culture supernatant samples
• Designed for vascular injury, fibrosis, inflammation, and regenerative research

Benefits:

• Provides a detailed molecular profile of vascular damage and repair mechanisms
• Supports evaluation of therapeutic interventions targeting vascular inflammation and remodeling
• Facilitates monitoring of angiogenic and fibrotic responses in preclinical rat models
• Enhances understanding of immune cell recruitment and cytokine signaling in vascular pathology
• Streamlines experimental workflows with high-throughput, multi-analyte capability

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.