270369
1,1,2-Trichlorotrifluoroethane
HPLC grade, ≥99.9%
Synonym(s):
1,1,2-Trichloro-1,2,2-trifluoroethane, 1,1,2-Trichloro-trifluoroethane, Genetron® 113
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About This Item
Linear Formula:
ClCF2CCl2F
CAS Number:
Molecular Weight:
187.38
EC Number:
200-936-1
UNSPSC Code:
12190000
PubChem Substance ID:
Beilstein/REAXYS Number:
1740335
MDL number:
grade
HPLC grade
vapor density
6.5 (vs air)
vapor pressure
5.5 psi ( 20 °C)
assay
≥99.9%
form
liquid
autoignition temp.
1256 °F
technique(s)
HPLC: suitable
impurities
<0.010% water
evapn. residue
<0.0005%
refractive index
n20/D 1.358 (lit.)
bp
47-48 °C (lit.)
mp
−35 °C (lit.)
density
1.57 g/mL at 25 °C (lit.)
λ
H2O reference
UV absorption
λ: 231 nm Amax: 1.00, λ: 240 nm Amax: 0.20, λ: 260-400 nm Amax: 0.01
SMILES string
FC(F)(Cl)C(F)(Cl)Cl
InChI
1S/C2Cl3F3/c3-1(4,6)2(5,7)8
InChI key
AJDIZQLSFPQPEY-UHFFFAOYSA-N
Packaging
Packaged under nitrogen, bottles are Sealed for Quality™
Legal Information
Genetron is a registered trademark of Honeywell International Inc.
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 2 - Eye Irrit. 2 - Ozone 1
Storage Class
10 - Combustible liquids
wgk
WGK 2
flash_point_f
383.0 °F
flash_point_c
195 °C
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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Yun-Ru Chen et al.
Oncotarget, 7(2), 1984-1999 (2015-12-18)
Macroautophagy can promote cellular survival or death depending on the cellular context and its extent. We hypothesized that autophagy induction would synergize with a therapeutic agent targeting the autophagic cargo. To test this hypothesis, we treated breast cancer MDA-MB-231 cells
Wei Chen et al.
Autophagy, 10(7), 1272-1284 (2014-06-07)
Ribonucleotide reductase (RNR) plays a critical role in catalyzing the biosynthesis and maintaining the intracellular concentration of 4 deoxyribonucleoside triphosphates (dNTPs). Unbalanced or deficient dNTP pools cause serious genotoxic consequences. Autophagy is the process by which cytoplasmic constituents are degraded
Y Michael et al.
International journal of pharmaceutics, 221(1-2), 165-174 (2001-06-09)
The nature of the drug-drug aggregation phenomena between salmeterol xinafoate and fluticasone propionate used in a metered-dose inhaler system has been examined. Interactions between the drugs in the solvents 1,1,2-trichlorotrifloroethane (CFC-113) and 1,1,1,2-tetrafluoroethane (HFA-134a) have been characterised using a focused