915033
TissueFab® bioink Bone
Vis/405 nm
Synonym(s):
3D Bioprinting, Bioink, GelMA, TissueFab
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About This Item
NACRES:
NA.23
UNSPSC Code:
12352201
Quality Level
description
0.2 μm sterile filtered, suitable for 3D bioprinting applications
form
gel form (viscous)
impurities
≤5 CFU/g Bioburden (Fungal), ≤5 CFU/g Bioburden (Total Aerobic)
color
white
pH
6.5-7.5
application(s)
3D bioprinting
storage temp.
2-8°C
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Application
TissueFab® - GelMA-Bone-Vis bioink is designed for promoting osteogenic differentiation of stem cells. It is based on Gelatin methacryloyl (GelMA) - Hydroxyapatite (HAp) hydrogel system. HAp is a highly crystalline form of calcium phosphate. HAp has a chemical similarity with the mineralized phase of bone which accounts for their excellent biocompatibility and osteoinductive and osteoconductive properties favorable for bone regeneration. HAp-containing hydrogels has been studied in literature to demonstrate their processability with different additive manufacturing approaches. Printing of cell laden structures with HAp containing bioink formulations have shown superior osteogenic properties.
Packaging
Product contains 10 ml of solution packaged in glass bottle.
Legal Information
TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
12 - Non Combustible Liquids
wgk
WGK 3
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Nano hydroxyapatite particles promote osteogenesis in a three-dimensional bio-printing construct consisting of alginate/gelatin/hASCs
Wang X F et al.
Royal Society of Chemistry Advances, 6, 6832-6842 (2016)
Tunable hydrogel composite with two-step processing in combination with innovative hardware upgrade for cell-based threedimensional bioprinting.
Wust S. et al.
Acta Biomaterialia, 10, 630-640 (2014)
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Materials science & engineering. C, Materials for biological applications, 49, 835-843 (2015-02-18)
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Materials (Basel, Switzerland), 9(4) (2016-04-14)
The concept of biphasic or multi-layered compound scaffolds has been explored within numerous studies in the context of cartilage and osteochondral regeneration. To date, no system has been identified that stands out in terms of superior chondrogenesis, osteogenesis or the
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