P50900
Propargylamine
98%
Synonym(s):
2-Propynylamine, 3-Amino-1-propyne
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About This Item
Linear Formula:
HC≡CCH2NH2
CAS Number:
Molecular Weight:
55.08
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
219-513-8
Beilstein/REAXYS Number:
773681
MDL number:
Assay:
98%
Quality Level
assay
98%
contains
≤2.5% water
refractive index
n20/D 1.449 (lit.)
bp
83 °C (lit.)
density
0.86 g/mL at 25 °C (lit.)
storage temp.
2-8°C
SMILES string
NCC#C
InChI
1S/C3H5N/c1-2-3-4/h1H,3-4H2
InChI key
JKANAVGODYYCQF-UHFFFAOYSA-N
Application
Synthesis of a chiral, fluorescent macrocycle by 1,3-dipolar cycloaddition of propargyl amides of carbohydrate-linked amino acids and 9,10-bis(azidomethyl)anthracene.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B
Storage Class
3 - Flammable liquids
wgk
WGK 3
flash_point_f
42.8 °F - closed cup
flash_point_c
6 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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Irene Bolea et al.
Journal of neural transmission (Vienna, Austria : 1996), 120(6), 893-902 (2012-12-15)
Alzheimer's disease (AD) is a complex neurodegenerative disorder with a multifaceted pathogenesis. There are at present three Food and Drug Administration-approved drugs based on the "one drug, one target" paradigm (donepezil, galantamine and rivastigmine) that improve symptoms by inhibiting acetylcholinesterase.
Synthesis, 3141-3141 (2006)
Claudio Gnaccarini et al.
Organic & biomolecular chemistry, 10(27), 5258-5265 (2012-06-02)
Transglutaminases (TGases) catalyse the transamidation of glutamine residues with primary amines. Herein we report the first FRET-based activity assay for the direct detection of the ligation (transamidation) reaction mediated by tissue TGase (TG2). This novel assay was then used in