156248
Sodium ethoxide
95%, powder
Synonym(s):
Sodium ethylate
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About This Item
Linear Formula:
CH3CH2ONa
CAS Number:
Molecular Weight:
68.05
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Beilstein/REAXYS Number:
3593646
Assay:
95%
Form:
powder
Product Name
Sodium ethoxide, 95%
vapor density
1.6 (vs air)
Quality Level
vapor pressure
<0.1 mmHg ( 20 °C)
assay
95%
form
powder
SMILES string
[Na+].CC[O-]
InChI
1S/C2H5O.Na/c1-2-3;/h2H2,1H3;/q-1;+1
InChI key
QDRKDTQENPPHOJ-UHFFFAOYSA-N
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General description
Sodium ethoxide (Sodium ethylate) is a sodium alkoxide. It has been synthesized by reacting sodium with ethanol. It undergoes decomposition in the presence of water to afford ethanol and sodium hydroxide. It is widely employed as a strong base in organic synthesis studies.
Application
- Organic solvent fractionation in lignin depolymerization: A study focused on enhancing the monophenolic yield of lignin depolymerization using a dualistic aprotic solvent system, employing sodium ethoxide for effective organic solvent fractionation. This approach underscores the versatility of sodium ethoxide in complex organic synthesis and biomass processing (Xu et al., 2024).
- Solid-state self-quenching-resistant sulfur dots: Research on sulfur dots utilized a solvent-type passivation strategy to control solid-state self-quenching-resistant behavior, where sodium ethoxide played a crucial role in the synthesis process. This study illustrates sodium ethoxides utility in advanced materials synthesis, particularly for optoelectronic applications (Wu et al., 2022).
- Synthesis of corrosion inhibitors: Sodium ethoxide was used in the efficient synthesis of 6,7-Dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile compounds, demonstrating its applicability as a base in the synthesis of corrosion inhibitors for steel alloys. This application combines computational and practical approaches to highlight sodium ethoxide′s role in materials science and corrosion prevention (Abd El-Lateef et al., 2022).
- Colon-targeted drug delivery systems: The design and synthesis of Thieno[2,3-b]pyridines-chitosan nanocomposites for colon targeting employed sodium ethoxide. This research showcases sodium ethoxides application in the preparation of targeted drug delivery systems, focusing on enhancing the efficacy and specificity of pharmaceutical treatments (Mansour et al., 2020).
- Synthesis of antimicrobial compounds: Sodium ethoxide was integral in the synthesis of novel bis-alpha,beta-unsaturated ketones and nicotinonitrile derivatives, aimed at antimicrobial applications. This study highlights the compound′s critical role in the development of new antimicrobial agents, demonstrating its utility in medicinal chemistry (Altalbawy, 2013).
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Sol. 1 - Self-heat. 1 - Skin Corr. 1A
Storage Class
4.2 - Pyrophoric and self-heating hazardous materials
flash_point_f
86.0 °F - closed cup
flash_point_c
30 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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James E Clark et al.
Circulation research, 93(2), e2-e8 (2003-07-05)
Carbon monoxide, which is generated in mammals during the degradation of heme by the enzyme heme oxygenase, is an important signaling mediator. Transition metal carbonyls have been recently shown to function as carbon monoxide-releasing molecules (CO-RMs) and to elicit distinct
Charanjit S Sethi et al.
Investigative ophthalmology & visual science, 46(1), 329-342 (2004-12-30)
To investigate glial remodeling and neuronal plasticity in adult human retinal detachment complicated by proliferative vitreoretinopathy (PVR) and to grade pathologic changes with a severity scoring system. Sixteen full-thickness retinectomy specimens obtained at retinal relaxing surgery for PVR were fixed
C Mazzitelli et al.
Journal of dental research, 87(2), 186-190 (2008-01-26)
The chemo-mechanical surface treatment of fiber posts increases their bonding properties. The combined use of atomic force and confocal microscopy allows for the assessment and quantification of the changes on surface roughness that justify this behavior. Quartz fiber posts were
Frank Derosa et al.
The Journal of organic chemistry, 73(3), 1139-1142 (2008-01-11)
Despite over a century of reports to the contrary, sodium methoxide has been found to react with nitric oxide (NO). The reaction, whose final organic product is sodium formate, is postulated to occur via an intermediate O-bound diazeniumdiolate [CH3O-N(O)=NO-] that
Wisam H Hoidy et al.
Journal of oleo science, 59(5), 229-233 (2010-05-01)
Difatty acyl thiourea (DFAT), which has biological activities as antibiotics and antifungal, has been synthesized from palm oil and thiourea using sodium ethoxide as catalyst. Ethyl fatty ester (EFE) and glycerol were produced as by-products. The synthesis was carried out
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