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D047

(±)-SKF-38393 hydrochloride

≥98% (HPLC), D1 dopamine receptor agonist, crystalline

Synonym(s):

(±)-1-Phenyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine-7,8-diol hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C16H17NO2 · HCl
CAS Number:
62717-42-4
Molecular Weight:
291.77
UNSPSC Code:
12352200
PubChem Substance ID:
24277907
NACRES:
NA.77
MDL number:
MFCD00069248
Assay:
≥98% (HPLC)
Form:
crystalline
Quality level:
100
Storage condition:
desiccated, protect from light
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Product Name

(±)-SKF-38393 hydrochloride, crystalline, ≥98% (HPLC)

Quality Level

100

assay

≥98% (HPLC)

form

crystalline

storage condition

desiccated, protect from light

color

white

solubility

H2O: >5 mg/mL, aqueous base: soluble (unstable)

SMILES string

Cl.Oc1cc2CCNCC(c3ccccc3)c2cc1O

InChI

1S/C16H17NO2.ClH/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11;/h1-5,8-9,14,17-19H,6-7,10H2;1H

InChI key

YEWHJCLOUYPAOH-UHFFFAOYSA-N

Gene Information

human ... DRD1(1812)

Application

(±)-SKF-38393 hydrochloride has been used as a selective D1 receptor agonist as a part of dopaminergic treatment. It has also been used to study its effect on prolactin in male baboons.

Biochem/physiol Actions

(±)-SKF-38393 is a D1 dopamine receptor agonist. It is known to promote the production of glutamate in the hippocampus.

Disclaimer

This material is hygroscopic. Air-sensitive. Light-sensitive.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000506644
0000506644
0000465127
0000465125
0000465125

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Stimulation of dopamine D1 receptor improves learning capacity in cooperating cleaner fish
Messias JPM, et al.
Proc. Royal Soc. Lond. B., 283(1823), 20152272-20152272 (2016)
The D1 dopamine receptor agonist SKF-38393 stimulates the release of glutamate in the hippocampus
Bouron A and Reuter H
Neuroscience, 94(4), 1063-1070 (1999)
Dopamine disruption increases cleanerfish cooperative investment in novel client partners
Soares MC, et al.
Royal Society open science, 4(5), 160609-160609 (2017)
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