L6135
Lectin from Arachis hypogaea (peanut)
biotin conjugate, lyophilized powder
Synonym(s):
PNA, Peanut agglutinin
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
NACRES:
NA.32
UNSPSC Code:
12352202
Form:
lyophilized powder
Mol wt:
120 kDa
conjugate
biotin conjugate
form
lyophilized powder
mol wt
120 kDa
composition
Protein, ≥80% Lowry
extent of labeling
~3 mol biotin per mol protein
technique(s)
blood typing: suitable, fractionation: suitable
solubility
water: 1.00-1.10 mg/mL, clear to slightly hazy, colorless
storage temp.
2-8°C
Quality Level
Looking for similar products? Visit Product Comparison Guide
General description
Peanut lectin (PNA) is a lectin or an agglutinin from the legume, Arachis hypogaea, found in peripheral venous blood in humans after ingestion of peanuts. PNA lectin is specific to the galactosyl (β-1,3) N-acetylgalactosamine.
Application
Lectin from Arachis hypogaea (peanut) has been used:
- in enzyme-linked micro plate assay to detect β-D-galactose-N-acetylglucosamine
- in Immunohistochemical double staining
- Immunohistochemical double staining for the detection of germinal centers
- in enzyme-linked microplate assayto detect β-D-galactose-N-acetylglucosamine
Biochem/physiol Actions
PNA does not agglutinate normal human erythrocytes, but strongly agglutinates neuraminidase treated erythrocytes. PNA has potent anti-T activity similar to the anti-T antibody in human sera. The lectin can be used to distinguish between human lymphocyte subsets.
Lectin from Arachis hypogaea (peanut) functions as an antigenic determinant for Thomsen-Friedenreich antigen (TF) and as mitogen for colorectal cancer stimulation cell division in normal colonic epithelium. It is therefore used as tumor marker.
Packaging
Package size based on protein content.
Physical form
Contains sodium citrate
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Peanut lectin stimulates proliferation of colon cancer cells by interaction with glycosylated CD44v6 isoforms and consequential activation of c-Met and MAPK: functional implications for disease-associated glycosylation changes
Glycobiology, 16(7), 594-601 (2006)
Andreia Valença et al.
Experimental eye research, 202, 108292-108292 (2020-10-17)
Careful control of iron availability in the retina is central to maintenance of iron homeostasis, as its imbalance is associated with oxidative stress and the progression of several retinopathies. Ferritin, known for its role in iron storage and detoxification, has
Dendritic cells are crucial for maintenance of tertiary lymphoid structures in the lung of influenza virus--infected mice
GeurtsvanKessel CH, et al.
The Journal of Experimental Medicine, 206, 2339-2349 (2009)
In situ observation of germinal center cell apoptosis during a secondary immune response
Saitoh HA, et al.
Journal of Clinical and Experimental Hematopathology : JCEH, 46, 73-82 (2006)
Peanut (Arachis hypogaea) lectin recognizes α−linked galactose, but not N-acetyl lactosamine in N-linked oligosaccharide terminals
Chacko BK and Appukuttan PS
International Journal of Biological Macromolecules, 28, 365-371 (2001)
Related Content
Product Information Sheet
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service