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Merck

SAB4700595

Monoclonal Anti-CD154 antibody produced in hamster

clone MR-1, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-CD40L, Anti-Cd40lg

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
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Product Name

Monoclonal Anti-CD154 antibody produced in hamster, clone MR-1, purified immunoglobulin, buffered aqueous solution

biological source

hamster

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

MR-1, monoclonal

form

buffered aqueous solution

species reactivity

mouse

concentration

1 mg/mL

technique(s)

flow cytometry: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

Gene Information

mouse ... Cd40lg(21947)

Related Categories

Application

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 4 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

The hamster monoclonal antibody MR-1 detects mouse CD154 / CD40L (CD40-ligand), a 39 kDa cell surface glycoprotein expressed predominantly on activated CD4+ lymphocytes.

Immunogen

Activated mouse Th1 clone D16

Physical form

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable


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Susana G Santos et al.
The Journal of biological chemistry, 279(51), 53062-53070 (2004-10-09)
Knowledge of the origin and biochemical status of beta(2)-microglobulin-free or misfolded major histocompatibility complex (MHC)-I molecules is essential for understanding their pleiotropic properties. Here we show that in normal human T cells, misfolding of MHC-I molecules is turned on upon

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