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SML3101

MLi-2

≥98% (HPLC), selective leucine-rich repeat kinase 2 (LRRK2) inhibitor, powder

Synonym(s):

cis-2,6-Dimethyl-4-(6-(5-(1-methylcyclopropoxy)-1H-indazol-3-yl)pyrimidin-4-yl)morpholine, rel-3-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-pyrimidinyl]-5-[(1-methylcyclopropyl)oxy]-1H-iIndazole

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About This Item

Empirical Formula (Hill Notation):
C21H25N5O2
CAS Number:
1627091-47-7
Molecular Weight:
379.46
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD30536362
Assay:
≥98% (HPLC)
Form:
powder
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Product Name

MLi-2, ≥98% (HPLC)

Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

C[C@]([H])(O[C@@]([H])(C1)C)CN1C2=CC(C3=NNC(C3=C4)=CC=C4OC5(C)CC5)=NC=N2

InChI key

ATUUNJCZCOMUKD-OKILXGFUSA-N

Biochem/physiol Actions

CNS active, highly potent and selective LRRK2 inhibitor
MLi-2 is an orally available, CNS active, highly potent and selective leucine-rich repeat kinase 2 (LRRK2) inhibitor. MLi-2 potently inhibits central and peripheral LRRK2 in mice.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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