108898
4-Nitro-o-phenylenediamine
98%
Synonym(s):
1,2-Diamino-4-nitrobenzene
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Linear Formula:
O2NC6H3(NH2)2
CAS Number:
Molecular Weight:
153.14
NACRES:
NA.22
PubChem Substance ID:
eCl@ss:
39030501
UNSPSC Code:
12352100
EC Number:
202-766-3
MDL number:
Beilstein/REAXYS Number:
608106
Assay:
98%
InChI key
RAUWPNXIALNKQM-UHFFFAOYSA-N
InChI
1S/C6H7N3O2/c7-5-2-1-4(9(10)11)3-6(5)8/h1-3H,7-8H2
SMILES string
Nc1ccc(cc1N)[N+]([O-])=O
assay
98%
mp
199-201 °C (lit.)
solubility
1 N HCl: ethanol, 1:1: soluble 50 mg/mL
functional group
nitro
Quality Level
Looking for similar products? Visit Product Comparison Guide
Related Categories
Application
4-Nitro-o-phenylenediamine was used to study the in vitro activation of 4-nitro-o-phenylenediamine into a potent mutagen in Salmonella typhimurium strain TA98 .
Biochem/physiol Actions
4-Nitro-o-phenylenediamine is a direct-acting mutagen.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Nahid Mashkouri Najafi et al.
Analytica chimica acta, 714, 82-88 (2012-01-17)
Herein, ultrasound-assisted emulsification microextraction (USAEME) and dispersive liquid-liquid microextraction (DLLME) methods based on applying low-density organic solvents have been critically compared for the speciation of inorganic selenium, Se(IV) (selenite) and Se(VI) (selenate) in environmental water samples by gas chromatography-flame ionization
S J Toering et al.
Mutation research, 361(2-3), 81-87 (1996-12-12)
Aromatic amines are activated into mutagens by both animal and plant systems. For plant-activated aromatic amines an important step in this process involves peroxidase enzymes. 4-nitro-o-phenylenediamine (NOP) is a well known direct-acting mutagen that can be enhanced in mutagenic potency
E A Varanda et al.
Teratogenesis, carcinogenesis, and mutagenesis, 19(6), 403-413 (1999-12-10)
The antimutagenic effect of ethanolic extract of propolis (EEP) and honeybee (Apis mellifera) venom, both collected in the State of São Paulo, Brazil, was assessed by the Salmonella/microsome assay upon direct- and indirect-acting mutagens. EEP had inhibitory effect (in an
J M Gentile et al.
Mutation research, 250(1-2), 79-86 (1991-09-01)
Chlorophyllin, the sodium and copper salt of chlorophyll, chlorophyll a, and chlorophyll b were tested for their ability to inhibit the mutagenic activity of the direct-acting mutagen 4-nitro-o-phenylenediamine (NOP) and its plant-activated mutagenic enhancement. All three forms of chlorophyll were
K Kaur et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 40(10), 1475-1482 (2002-10-22)
The antimutagenic effect of benzene, chloroform, acetone and methanol fractions from Terminalia arjuna, a well-known medicinal plant, was determined against Acid Black dye, 2-aminofluorene (2AF) and 4-nitro-o-phenylenediamine (NPD) in TA98 Frameshift mutagen tester strain of Salmonella typhimurium. Among the different
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service