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168734

4,4′-Dihydroxybiphenyl

Name: 4,4′-Dihydroxybiphenyl
Brand: ALDRICH

97%

Synonym(s):

4,4′-Biphenol, 4,4′-Biphenyldiol, 4,4′-Diphenol

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About This Item

Linear Formula:

HOC₆H₄C₆H₄OH

CAS Number:

92-88-6

Molecular Weight:

186.21

UNSPSC Code:

12162002

NACRES:

NA.23

PubChem Substance ID:

24850252

EC Number:

202-200-5

Beilstein/REAXYS Number:

1908886

MDL number:

MFCD00002348

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Properties

assay

97%

form

powder

mp

280-282 °C (lit.)

SMILES string

Oc1ccc(cc1)-c2ccc(O)cc2

InChI

1S/C12H10O2/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10/h1-8,13-14H

InChI key

VCCBEIPGXKNHFW-UHFFFAOYSA-N

Gene Information

human ... ESR1(2099), ESR2(2100), MMP3(4314)

Description

Application

Used in the preparation of polyether liquid crystals.

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pictograms

GHS02,GHS07

signalword

Warning

hcodes

H252,H317,H412

pcodes

P235 - P261 - P272 - P273 - P280 - P302 + P352

Hazard Classifications

Aquatic Chronic 3 - Self-heat. 2 - Skin Sens. 1

Storage Class

4.2 - Pyrophoric and self-heating hazardous materials

wgk

WGK 2

flash_point_f

537.8 °F

flash_point_c

281 °C

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Angewandte Chemie (International Edition in English), 106, 1563-1563 (1994)

Inhibition of melanogenic activity by 4,4'-dihydroxybiphenyl in melanoma cells.

Jae Kyung No et al.

Biological & pharmaceutical bulletin, 29(1), 14-16 (2006-01-06)

In our previous study, we showed that 4,4'-dihydroxybiphenyl (44'-BP) reduced melanin content via the inhibition of tyrosinase. In the current study, we utilized 44'-BP treated B16 melanoma cells (B16 cells) to measure several key cellular parameters known to be involved

Metabolism of biphenyl by Aspergillus toxicarius: induction of hydroxylating activity and accumulation of water-soluble conjugates.

J H Golbeck et al.

Journal of bacteriology, 156(1), 49-57 (1983-10-01)

Biphenyl metabolism in Aspergillus toxicarius occurs by successive hydroxylations in the 4- and 4'-positions, followed by conjugation with sulfate to produce 4-hydroxybiphenyl-O-sulfonic acid and 4,4'-dihydroxybiphenyl-O-sulfonic acid. The hydroxylation reactions normally occur only after a prolonged lag period after which the

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