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Merck

239968

trans-Cinnamaldehyde

≥99%

Synonym(s):

trans-3-Phenyl-2-propenal

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About This Item

Linear Formula:
C6H5CH=CHCHO
CAS Number:
14371-10-9
Molecular Weight:
132.16
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24854395
MDL number:
MFCD00007000
Beilstein/REAXYS Number:
1071571
Assay:
≥99%
Form:
liquid

Key Documents

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InChI

1S/C9H8O/c10-8-4-7-9-5-2-1-3-6-9/h1-8H/b7-4+

SMILES string

[H]C(=O)\C=C\c1ccccc1

InChI key

KJPRLNWUNMBNBZ-QPJJXVBHSA-N

vapor density

4.6 (vs air)

assay

≥99%

form

liquid

Quality Level

200

bp

250-252 °C (lit.)

mp

−9-−4 °C (lit.)

density

1.05 g/mL at 25 °C (lit.)

functional group

aldehyde, phenyl

storage temp.

2-8°C

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General description

The neuroprotective and anti-inflammatory effects of trans-cinnamaldehyde (TCA) were studied.

Application

trans-Cinnamaldehyde was used to study the useful amino groups at aminosilanized surface.

pictograms

Exclamation mark
GHS07

signalword

Warning

Storage Class

10 - Combustible liquids

flash_point_f

159.8 °F - closed cup

flash_point_c

71 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

hcodes

H317

Hazard Classifications

Skin Sens. 1A

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Certificates of Analysis (COA)

Lot/Batch Number
S8421105
STBL2199
STBJ1063
STBF1530V
STBG0250V

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Ji-Hi Pyo et al.
Biological & pharmaceutical bulletin, 36(12), 1928-1935 (2013-12-03)
The anti-inflammatory and neuroprotective effects of trans-cinnamaldehyde (TCA) were investigated on the inflammatory cells and the dopaminergic degeneration in mice. TCA inhibited the up-regulation of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in the lipopolysaccharide (LPS)-induced inflammatory BV2 microglial
Wen-Xian Du et al.
Journal of agricultural and food chemistry, 60(32), 7799-7804 (2012-07-27)
The addition of plant essential oils to edible films and coatings has been shown to protect against bacterial pathogens and spoilage while also enhancing sensory properties of foods. This study evaluated the effect of adding 0.5 and 0.75% carvacrol (active
Jeyachchandran Visvalingam et al.
Applied and environmental microbiology, 79(3), 942-950 (2012-11-28)
Cinnamaldehyde is a natural antimicrobial that has been found to be effective against many food-borne pathogens, including Escherichia coli O157:H7. Although its antimicrobial effects have been well investigated, limited information is available on its effects at the molecular level. Sublethal
Amrita A Nagle et al.
PloS one, 7(11), e50125-e50125 (2012-11-28)
Multifunctional trans-cinnamaldehyde (CA) and its analogs display anti-cancer properties, with 2-benzoyloxycinnamaldehyde (BCA) and 5-fluoro-2-hydroxycinnamaldehyde (FHCA) being identified as the ortho-substituted analogs that possess potent anti-tumor activities. In this study, BCA, FHCA and a novel analog 5-fluoro-2-benzoyloxycinnamaldehyde (FBCA), were demonstrated to
Marie E Barabas et al.
PloS one, 7(10), e47988-e47988 (2012-11-08)
Subpopulations of somatosensory neurons are characterized by functional properties and expression of receptor proteins and surface markers. CGRP expression and IB4-binding are commonly used to define peptidergic and non-peptidergic subpopulations. TRPA1 is a polymodal, plasma membrane ion channel that contributes
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