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Merck

324787

2,2,2-Trifluoroethanesulfonyl chloride

99%

Synonym(s):

Tresyl chloride

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About This Item

Linear Formula:
CF3CH2SO2Cl
CAS Number:
1648-99-3
Molecular Weight:
182.55
UNSPSC Code:
12352101
NACRES:
NA.22
PubChem Substance ID:
24859467
EC Number:
216-713-7
Beilstein/REAXYS Number:
1860983
MDL number:
MFCD00007458
Assay:
99%
Form:
liquid

Key Documents

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InChI key

CXCHEKCRJQRVNG-UHFFFAOYSA-N

InChI

1S/C2H2ClF3O2S/c3-9(7,8)1-2(4,5)6/h1H2

SMILES string

FC(F)(F)CS(Cl)(=O)=O

assay

99%

form

liquid

refractive index

n20/D 1.388 (lit.)

bp

140-141 °C (lit.), 64-67 °C/45 mmHg (lit.)

density

1.651 g/mL at 25 °C (lit.)

functional group

fluoro

storage temp.

2-8°C

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Related Categories

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H314

Hazard Classifications

Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

161.6 °F - closed cup

flash_point_c

72 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX4599
0000089619
0000074625
0000081415
0000038412

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K I Allam et al.
Analytical biochemistry, 162(1), 171-177 (1987-04-01)
A stable T-2 hydrazide gel is prepared by activating T-2 toxin with tresyl chloride followed by coupling to agarose-adipic acid hydrazide. Utilized as an affinity chromatography column, this T-2 hydrazide gel purifies a monoclonal antibody for T-2 in high yield
K Nakamura et al.
Journal of chromatography, 510, 101-113 (1990-06-27)
A new activated support TSK gel Tresyl-5PW was evaluated for the coupling of antibodies, which was found to occur easily under mild conditions with high yields. Optimum coupling conditions were a 2-h reaction at 25 degrees C in 1 M
Jie Mei et al.
Electrophoresis, 29(18), 3825-3833 (2008-08-30)
A novel covalent coupling method for coating of capillaries with liposomes has been developed, which includes three steps: (i) epoxy-diol coating, (ii) activation with 2,2,2-trifluoroethanesulfonyl chloride, and (iii) liposome coupling. The coating conditions, such as the reaction time and temperature
Markus Gantert et al.
Pharmaceutical research, 26(3), 529-538 (2008-11-19)
The challenge in developing liposomes to be used in active drug targeting is to design a method that can be used for modifying liposomal membranes that is applicable for a number of different specific ligands. In this study, the post
C F Mandenius et al.
Analytical biochemistry, 137(1), 106-114 (1984-02-01)
Two methods for the chemical binding of biomolecules to silicon surfaces are described. The first method utilizes an alkyl silane and a nucleophilic reagent to join the biomolecule to the silicon surface; the second method involves crosslinking with glutaraldehyde in
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