382310
Didecyldimethylammonium bromide
98%
Synonym(s):
DDAB
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About This Item
Linear Formula:
[CH3(CH2)9]2N(CH3)2Br
CAS Number:
Molecular Weight:
406.53
UNSPSC Code:
12352116
NACRES:
NA.22
PubChem Substance ID:
EC Number:
219-234-1
Beilstein/REAXYS Number:
6492993
MDL number:
InChI key
UMGXUWVIJIQANV-UHFFFAOYSA-M
InChI
1S/C22H48N.BrH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1
SMILES string
[Br-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC
assay
98%
Quality Level
reaction suitability
core: ammonium
mp
149-151 °C (lit.)
form
powder
Related Categories
Application
Didecyldimethylammonium bromide (DDAB) is commonly used as a surfactant and a phase transfer catalyst. It is also used in the preparation of hydrophobic ammonium-based ionic liquid.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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C Carbone et al.
Colloids and surfaces. B, Biointerfaces, 167, 337-344 (2018-04-24)
In this work, we aimed at developing an improved topical SLN formulation combining itraconazole delivery with a coating layer of didodecyldimethylammonium bromide, thus repurposing the drug effectiveness by synergistic skin anticancer effectiveness. In order to obtain a stable SLN formulation
Jie Qu et al.
Drug delivery, 23(9), 3408-3416 (2016-05-18)
Glioblastoma is a malignant brain tumor originating in the central nervous system. Successfully therapy of this disease required the efficient delivery of therapeutic agents to the tumor cells and tissues. Delivery of anticancer drugs using novel nanocarriers is promising in
Chiara Botto et al.
International journal of pharmaceutics, 516(1-2), 334-341 (2016-11-28)
Solid lipid nanoparticles (SLNs) may be considered as a new approach for therapeutics for many diseases. In addition to drug delivery, their use as non-viral vectors for gene delivery can be obtained by including cationic lipids, which provide a positive
Christopher J Ioannou et al.
Antimicrobial agents and chemotherapy, 51(1), 296-306 (2006-10-25)
Mode-of-action studies concluded that alkyldimethylbenzylammonium chloride (ADBAC) (a blend of C(12), C(14) and C(16) alkyl homologues) and didecyldimethylammonium chloride (DDAC) are both membrane-active agents, possessing subtly different modes of action reflecting early cell interactions against Staphylococcus aureus. ADBAC and DDAC
Chunhui Lai et al.
Theranostics, 8(6), 1723-1739 (2018-03-21)
Dendritic cell (DC)-based cancer vaccines is a newly emerging and potent form of immune therapy. As for any new technology, there are still considerable challenges that need to be addressed. Here, we investigate the antitumor potential of a novel liposomal
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