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Merck

H45132

5-Hydroxy-Nω-methyltryptamine oxalate

99%

Synonym(s):

3-(2-Methylaminoethyl)indol-5-ol oxalate, N-Methylserotonin oxalate

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About This Item

Empirical Formula (Hill Notation):
C13H16N2O5
CAS Number:
1975-81-1
Molecular Weight:
280.28
NACRES:
NA.22
PubChem Substance ID:
24895517
UNSPSC Code:
12352100
MDL number:
MFCD00013159
Assay:
99%

Key Documents

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InChI

1S/C11H14N2O.C2H2O4/c1-12-5-4-8-7-13-11-3-2-9(14)6-10(8)11;3-1(4)2(5)6/h2-3,6-7,12-14H,4-5H2,1H3;(H,3,4)(H,5,6)

SMILES string

OC(=O)C(O)=O.CNCCc1c[nH]c2ccc(O)cc12

InChI key

DYOZWAJOUTVNAF-UHFFFAOYSA-N

assay

99%

mp

161-162 °C (dec.) (lit.)

Quality Level

100

Related Categories

Application

  • reactant for preparation of 5-HT receptor agonists

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
STBK4365
STBJ0547
STBG1582V
STBD1637V
STBC1719V

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A R Johnston et al.
Experimental brain research, 93(2), 293-298 (1993-01-01)
The effects of 5-hydroxytryptamine (5-HT) and related compounds on the discharge rate of tonically active medial vestibular nucleus (MVN) neurones were studied in an in vitro slice preparation of the dorsal brainstem of the rat. The majority (87 of 107
G L Laekeman et al.
Agents and actions, 16(5), 443-445 (1985-07-01)
Pharmacological effects of 5-hydroxykynuramine (5-HK) were investigated in chicken whole blood. It was shown that 5-HK had a time-depending inhibiting activity on platelet aggregation induced by 5-hydroxytryptamine (5-HT). Experiments were carried out in order to determine whether the inhibitory effect
D Alberghina et al.
Research in veterinary science, 90(3), 392-395 (2010-07-17)
To evaluate the changes in plasma and platelet serotonin (5-HT) as markers of the serotoninergic system in equines, 5-HT content was measured by high performance liquid chromatography (HPLC) in deproteinized plasma obtained from peripheral blood samples of 12 clinically healthy
Simultaneous micro-determination of serotonin and 5-hydroxyindole-3-acetic acid with 5-hydroxy-N omega-methyltryptamine, as an internal standard, in biological materials by high-performance liquid chromatography with electrochemical detection.
K Shibata et al.
Journal of chromatography, 430(2), 381-387 (1988-09-09)
Albrecht Pfäfflin et al.
Annals of clinical biochemistry, 46(Pt 2), 146-148 (2009-01-20)
Serotonin is frequently analysed by high-performance liquid chromatography (HPLC) with electrochemical detection. However, the accuracy of these methods may be affected by the presence of certain drugs. We describe for the first time the interference of paracetamol in therapeutic dosages
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