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870600P

Avanti

PAzePC

Avanti Research™ - A Croda Brand

Synonym(s):

1-palmitoyl-2-azelaoyl-sn-glycero-3-phosphocholine

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About This Item

Empirical Formula (Hill Notation):
C33H64NO10P
CAS Number:
117746-89-1
Molecular Weight:
665.84
MDL number:
MFCD03412020
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

PAzePC, Avanti Research™ - A Croda Brand 870600P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (870600P-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 870600P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCC(O)=O)=O)COC(CCCCCCCCCCCCCCC)=O)=O

InChI

1S/C33H64NO10P/c1-5-6-7-8-9-10-11-12-13-14-15-18-21-24-32(37)41-28-30(29-43-45(39,40)42-27-26-34(2,3)4)44-33(38)25-22-19-16-17-20-23-31(35)36/h30H,5-29H2,1-4H3,(H-,35,36,39,40)/t30-/m1/s1

InChI key

GHQQYDSARXURNG-SSEXGKCCSA-N

General description

1-palmitoyl-2-azelaoyl-sn-glycero-3-phosphocholine (PAzePC) structure contains an anionic carboxyl group at the end of the short, oxidized acyl chain.

Application

1-palmitoyl-2-azelaoyl-sn-glycero-3-phosphocholine (PazePC) may be used as an oxidized lipid dopant in liposomes for examining the link between the permeation of H2O2 and the structure of lipid membranes. It may also be used as lysosomal phospholipase A2 substrate in the study of structural basis for Zn2+ mediated inhibition of lysosomal phospholipase A2.

Biochem/physiol Actions

1-palmitoyl-2-azelaoyl-sn-glycero-3-phosphocholine (PazePC) is a stable lipid oxidation product. It serves as an inter-H2O2 permeation promoter. It is the most common drug target for antipsychotic and antimicrobial agents in cells under oxidative stress at inflammatory sites.

Packaging

5 mL Amber Glass Screw Cap Vial (870600P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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