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999989C

Avanti

18:1 Diether PC

Avanti Research™ - A Croda Brand

Synonym(s):

Dioctadecenyl PC

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About This Item

Empirical Formula (Hill Notation):
C44H88NO6P
CAS Number:
105370-99-8
Molecular Weight:
758.15
MDL number:
MFCD28143676
UNSPSC Code:
51191904
NACRES:
NA.25
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Product Name

18:1 Diether PC, 1,2-di-O-(9Z-octadecenyl)-sn-glycero-3-phosphocholine, chloroform

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (999989C-10mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 999989C

concentration

10 mg/mL (999989C-10mg)

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCCCCCCC/C=C\CCCCCCCC)COCCCCCCCC/C=C\CCCCCCCC)=O

InChI

1S/C44H88NO6P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-39-48-42-44(43-51-52(46,47)50-41-38-45(3,4)5)49-40-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h20-23,44H,6-19,24-43H2,1-5H3/b22-20-,23-21-/t44-/m1/s1

InChI key

RBPWQIKZHBYIEY-PXCYNBOKSA-N

General description

18:1 Diether PC (phosphocholine) is a class of glycerophospholipids that has two octadecene chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It has choline as the alcohol moiety, attached to the phosphate group.

Application

18:1 Diether PC or 1,2-di-O-(9Z-octadecenyl)-sn-glycero-3-phosphocholine might be used:
  • to prepare proteoliposomes to investigate the effects of ceramide and ceramide phosphate/ for the determination of phospholipase A activity of lecithin-cholesterol acyltransferase (LCAT) in the ether matrix
  • to prepare lipid bilayer membrane to study the influence of glutamic acid residues and pH on the properties of transmembrane helices
  • in large unilamellar vesicles (LUVs) to explore the differential interaction of pH (low) insertion peptide (pHLIP) with it by utilizing fluorescence and circular dichroism (CD) spectroscopic approaches

Biochem/physiol Actions

Lipids prepared using 18:1 Diether PC (phosphocholine), are found to be more stable than the natural ester lipids under alkaline conditions.

Packaging

5 mL Clear Glass Sealed Ampule (999989C-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk

WGK 3

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

flash_point_f

does not flash

flash_point_c

does not flash

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