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999989P

Avanti

18:1 Diether PC

Name: 18:1 Diether PC
Brand: AVANTI

Avanti Research^™ - A Croda Brand

Synonym(s):

1,2-di-O-(9Z-octadecenyl)-sn-glycero-3-phosphocholine

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About This Item

Empirical Formula (Hill Notation):

C₄₄H₈₈NO₆P

CAS Number:

105370-99-8

Molecular Weight:

758.15

MDL number:

MFCD28143676

UNSPSC Code:

51191904

NACRES:

NA.25

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Properties

Product Name

18:1 Diether PC, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (999989P-10mg)

manufacturer/tradename

Avanti Research^™ - A Croda Brand 999989P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCCCCCCC/C=C\CCCCCCCC)COCCCCCCCC/C=C\CCCCCCCC)=O

InChI

1S/C44H88NO6P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-39-48-42-44(43-51-52(46,47)50-41-38-45(3,4)5)49-40-37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h20-23,44H,6-19,24-43H2,1-5H3/b22-20-,23-21-/t44-/m1/s1

InChI key

RBPWQIKZHBYIEY-PXCYNBOKSA-N

Description

General description

18:1 Diether PC (phosphocholine) is a class of glycerophospholipids that has two octadecene chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It has choline as the alcohol moiety, attached to the phosphate group.

Application

18:1 Diether PC or 1,2-di-O-(9Z-octadecenyl)-sn-glycero-3-phosphocholine might be used:

to prepare diether PC (phosphocholine)-containing proteoliposomes
to prepare lipid bilayer membrane, to study the influence of glutamic acid residues and pH on the properties of transmembrane helices
in large unilamellar vesicles (LUVs) to explore the differential interaction of pH (low) insertion peptide (pHLIP) with it by utilizing fluorescence and circular dichroism (CD) spectroscopic approaches

Biochem/physiol Actions

Lipids prepared using 18:1 Diether PC (phosphocholine), are found to be more stable than the natural ester lipids under alkaline conditions.

Packaging

5 mL Clear Glass Sealed Ampule (999989P-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Storage Class

11 - Combustible Solids

wgk

WGK 3

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