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999998P

Avanti

06:0 Diether PC

Avanti Research™ - A Croda Brand

Synonym(s):

1,2-di-O-hexyl-sn-glycero-3-phosphocholine

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About This Item

Empirical Formula (Hill Notation):
C20H44NO6P
CAS Number:
79645-39-9
Molecular Weight:
425.54
MDL number:
MFCD02259319
UNSPSC Code:
51191904
NACRES:
NA.25
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Product Name

06:0 Diether PC, Avanti Research™ - A Croda Brand 999998P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (999998P-10mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 999998P

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCCCCC)COCCCCCC)=O

InChI

1S/C20H44NO6P/c1-6-8-10-12-15-24-18-20(25-16-13-11-9-7-2)19-27-28(22,23)26-17-14-21(3,4)5/h20H,6-19H2,1-5H3/t20-/m1/s1

InChI key

IQYIEYGHUQSRSF-HXUWFJFHSA-N

General description

06:0 Diether PC (phosphocholine) is a glycerophospholipid having two hexane chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It has choline as the alcohol moiety, attached to the phosphate group.

Application

06:0 Diether PC or 1,2-di-O-hexyl-sn-glycero-3-phosphocholine might be used:
  • in bicelle media to measure the H—C one-bond residual dipolar couplings for trisaccharides, Lewis X (Lex) and Lewis A (Lea) methyl glycosides using nuclear magnetic resonance (NMR) residual dipolar couplings
  • to compose isotropically tumbling small bicelles, to study its size and morphology by 31P NMR and atomic force microscopy (AFM)
  • in bicelle preparation for NMR studies

Biochem/physiol Actions

06:0 Diether PC (phosphocholine) is useful for bicelles preparation. Bicelles can be integrated into standard crystallization protocols and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation. Incorporating 06:0 Diether PC in bicelles results in bicelles similar to conventional phospholipid bicelles but with improved chemical stability.

Packaging

5 mL Clear Glass Sealed Ampule (999998P-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Storage Class

11 - Combustible Solids

wgk

WGK 3

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