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About This Item
Empirical Formula (Hill Notation):
C20H44NO6P
CAS Number:
Molecular Weight:
425.54
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
Product Name
06:0 Diether PC, Avanti Research™ - A Croda Brand 999998P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (999998P-10mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 999998P
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCCCCC)COCCCCCC)=O
InChI
1S/C20H44NO6P/c1-6-8-10-12-15-24-18-20(25-16-13-11-9-7-2)19-27-28(22,23)26-17-14-21(3,4)5/h20H,6-19H2,1-5H3/t20-/m1/s1
InChI key
IQYIEYGHUQSRSF-HXUWFJFHSA-N
General description
06:0 Diether PC (phosphocholine) is a glycerophospholipid having two hexane chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It has choline as the alcohol moiety, attached to the phosphate group.
Application
06:0 Diether PC or 1,2-di-O-hexyl-sn-glycero-3-phosphocholine might be used:
- in bicelle media to measure the H—C one-bond residual dipolar couplings for trisaccharides, Lewis X (Lex) and Lewis A (Lea) methyl glycosides using nuclear magnetic resonance (NMR) residual dipolar couplings
- to compose isotropically tumbling small bicelles, to study its size and morphology by 31P NMR and atomic force microscopy (AFM)
- in bicelle preparation for NMR studies
Biochem/physiol Actions
06:0 Diether PC (phosphocholine) is useful for bicelles preparation. Bicelles can be integrated into standard crystallization protocols and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation. Incorporating 06:0 Diether PC in bicelles results in bicelles similar to conventional phospholipid bicelles but with improved chemical stability.
Packaging
5 mL Clear Glass Sealed Ampule (999998P-10mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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Storage Class
11 - Combustible Solids
wgk
WGK 3
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