48-680MAG
MILLIPLEX® Multi-Pathway Signaling Panel
Premixed Multi-Pathway Phosphoprotein 9-Plex Cell Signaling Panel
Synonym(s):
ERK Cell Signaling Assay, Luminex® Cell Signaling Assay, Millipore Cell Signaling Assay, MAPK STAT TCR assay, multi-pathway signaling panel, multi-target phosphorylation panel, phosphoprotein multiplex assay, rat cell signaling panel, rat intracellular signaling biomarkers
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About This Item
UNSPSC Code:
12161503
NACRES:
NA.47
eCl@ss:
32161000
Quality Level
species reactivity
rat, mouse, human
technique(s)
multiplexing: suitable
input
cell lysate
packaging
pkg of 1 ea
manufacturer/tradename
Milliplex®
detection method
fluorometric (Luminex® xMAP® technology)
shipped in
wet ice
storage temp.
2-8°C
General description
This panel includes phosphorylated proteins involved in multiple signaling pathways that regulate cell survival, proliferation, inflammation, and transcriptional activity. CREB (pS133) is a transcription factor activated by cAMP signaling. ERK (pT185/pY187), JNK (pT183/pY185), and p38 (Thr180/Tyr182) are key components of the MAPK pathway. Akt (pS473) regulates cell survival and metabolism. NFκB (pS536) controls inflammatory and immune responses. p70S6K (Thr412) is involved in protein synthesis, while STAT3 (pS727) and STAT5A/B (pY694/699) mediate cytokine signaling and immune regulation
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 9 analytes in human, mouse, or rat cell lysate samples.
Analytes Included: CREB (pS133), ERK (pT185/pY187), NFκB (pS536), JNK (pT183/pY185), p38 (Thr180/Tyr182), p70S6K (Thr412), STAT3 (pS727), STAT5A/B (pY694/699), Akt (pS473)
Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate™ Control Assays).
Analytes Included: CREB (pS133), ERK (pT185/pY187), NFκB (pS536), JNK (pT183/pY185), p38 (Thr180/Tyr182), p70S6K (Thr412), STAT3 (pS727), STAT5A/B (pY694/699), Akt (pS473)
Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate™ Control Assays).
Features and Benefits
- Simultaneously detect 9 phosphorylated proteins across multiple signaling pathways
- Covers key pathways including MAPK, STAT, Akt, and NFκB
- Magnetic bead-based format ensures reproducibility and efficient processing
- Compatible with cell lysates from diverse experimental conditions
- Ideal for signal transduction, oncology, immunology, and toxicology research
- Fast, convenient alternative to Western Blotting and immunoprecipitation procedures
Legal Information
Luminex is a registered trademark of Luminex Corp
MAPMATE is a trademark of Merck KGaA, Darmstadt, Germany
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
signalword
Danger
Storage Class
10 - Combustible liquids
wgk
WGK 3
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - ED ENV 1 - Eye Dam. 1 - Skin Irrit. 2
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 48-680MAG | 04053252294105 |
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