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About This Item
Linear Formula:
(HO)2C6H3CO2H
CAS Number:
Molecular Weight:
154.12
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
202-760-0
Beilstein/REAXYS Number:
1448841
MDL number:
grade
primary reference standard
shelf life
limited shelf life, expiry date on the label
manufacturer/tradename
HWI
mp
197-200 °C (dec.) (lit.)
application(s)
food and beverages
SMILES string
OC(=O)c1ccc(O)c(O)c1
InChI
1S/C7H6O4/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,8-9H,(H,10,11)
InChI key
YQUVCSBJEUQKSH-UHFFFAOYSA-N
General description
Protocatechuic acid belongs to the class of polyphenolic compounds, which can be generally isolated from the dried flower of roselle. It can serve as a potential candidate possessing anticancer property, which can be involved in suppressing the growth of human promyelocytic leukemia HL-60 cells.
Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.
Exact content by quantitative NMR can be found on the certificate.
Application
Reference Standard in the analysis of herbal medicinal products
Biochem/physiol Actions
Chemopreventive in several animal models of carcinogenesis. Blocks cell proliferation in the post-initiation phase.
Other Notes
This compound is commonly found in plants of the genus: allium carum cinnamomum curcuma ginkgo humulus melissa pimpinella thymus
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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T H Tseng et al.
Biochemical pharmacology, 60(3), 307-315 (2000-06-17)
Hibiscus protocatechuic acid (PCA), a phenolic compound isolated from the dried flower of Hibiscus sabdariffa L. (Malvaceae), demonstrated antioxidant and antitumor promotion effects in our previous study. In the present study, Hibiscus PCA was found to inhibit the survival of
In vivo protective effect of protocatechuic acid on tert-butyl hydroperoxide-induced rat hepatotoxicity
Liu C-L, et al.
Food And Chemical Toxicology, 40, 635-641 (2002)
Saravanan Palani et al.
eLife, 10 (2021-07-17)
Actin filaments are central to numerous biological processes in all domains of life. Driven by the interplay with molecular motors, actin binding and actin modulating proteins, the actin cytoskeleton exhibits a variety of geometries. This includes structures with a curved