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Merck

06536

trans-Cinnamaldehyde

analytical standard

Synonym(s):

trans-3-Phenyl-2-propenal

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About This Item

Linear Formula:
C6H5CH=CHCHO
CAS Number:
14371-10-9
Molecular Weight:
132.16
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
329748242
MDL number:
MFCD00007000
Beilstein/REAXYS Number:
1071571

Key Documents

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InChI

1S/C9H8O/c10-8-4-7-9-5-2-1-3-6-9/h1-8H/b7-4+

InChI key

KJPRLNWUNMBNBZ-QPJJXVBHSA-N

SMILES string

[H]C(=O)\C=C\c1ccccc1

grade

analytical standard

vapor density

4.6 (vs air)

assay

≥95.0% (GC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

Quality Level

100

bp

250-252 °C (lit.)

mp

−9-−4 °C (lit.)

density

1.05 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

format

neat

storage temp.

2-8°C

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Related Categories

Application


  • Pharmacological Activity in Metabolic Diseases: Cinnamaldehyde is investigated for its potential to attenuate diabetic osteoporosis in a rat model, mediated through the modulation of the netrin-1/DCC-UNC5B signaling pathway. This suggests its applicability in therapeutic strategies against metabolic bone diseases (Ji et al., 2024).

  • Antibacterial and Biofilm Inhibition: The study reviews the inhibitory effects of natural compounds, including cinnamaldehyde, on the quorum sensing systems of Pseudomonas aeruginosa. This indicates its potential role in managing biofilm communities, which could be crucial for developing new antibacterial strategies (Shariati et al., 2024).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

This compound is commonly found in plants of the genus: cinnamomum

pictograms

Exclamation mark
GHS07

signalword

Warning

Storage Class

10 - Combustible liquids

flash_point_f

159.8 °F - closed cup

flash_point_c

71 °C - closed cup

hcodes

H317

Hazard Classifications

Skin Sens. 1A

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM2306
BCCG7613
BCCB9410
BCBV1724
BCBT9263

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B Averbeck et al.
European journal of pain (London, England), 17(5), 724-734 (2012-11-10)
Thunberg's thermal grill produces a sensation of strong heat upon skin contact with spatially interlaced innocuous warm and cool stimuli. To examine the classes of peripheral axons that might contribute to this illusion, the effects of topical l-menthol, an activator
Amrita A Nagle et al.
PloS one, 7(11), e50125-e50125 (2012-11-28)
Multifunctional trans-cinnamaldehyde (CA) and its analogs display anti-cancer properties, with 2-benzoyloxycinnamaldehyde (BCA) and 5-fluoro-2-hydroxycinnamaldehyde (FHCA) being identified as the ortho-substituted analogs that possess potent anti-tumor activities. In this study, BCA, FHCA and a novel analog 5-fluoro-2-benzoyloxycinnamaldehyde (FBCA), were demonstrated to
Jeyachchandran Visvalingam et al.
Applied and environmental microbiology, 79(3), 942-950 (2012-11-28)
Cinnamaldehyde is a natural antimicrobial that has been found to be effective against many food-borne pathogens, including Escherichia coli O157:H7. Although its antimicrobial effects have been well investigated, limited information is available on its effects at the molecular level. Sublethal
Wen-Xian Du et al.
Journal of agricultural and food chemistry, 60(32), 7799-7804 (2012-07-27)
The addition of plant essential oils to edible films and coatings has been shown to protect against bacterial pathogens and spoilage while also enhancing sensory properties of foods. This study evaluated the effect of adding 0.5 and 0.75% carvacrol (active
Marie E Barabas et al.
PloS one, 7(10), e47988-e47988 (2012-11-08)
Subpopulations of somatosensory neurons are characterized by functional properties and expression of receptor proteins and surface markers. CGRP expression and IB4-binding are commonly used to define peptidergic and non-peptidergic subpopulations. TRPA1 is a polymodal, plasma membrane ion channel that contributes
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