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Merck

14668

Ellagic acid

analytical standard

Synonym(s):

4,4′,5,5′,6,6′-Hexahydroxydiphenic acid 2,6,2′,6′-dilactone, Alizarin Yellow, Benzoaric acid, Elagostasine, Eleagic acid, Gallogen, Lagistase

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About This Item

Empirical Formula (Hill Notation):
C14H6O8
CAS Number:
476-66-4
Molecular Weight:
302.19
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
329750574
EC Number:
207-508-3
Beilstein/REAXYS Number:
47549
MDL number:
MFCD00006914

Key Documents

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SMILES string

Oc1cc2C(=O)Oc3c(O)c(O)cc4C(=O)Oc(c1O)c2-c34

InChI key

AFSDNFLWKVMVRB-UHFFFAOYSA-N

InChI

1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H

grade

analytical standard

assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

impurities

≤12% water

application(s)

food and beverages

format

neat

storage temp.

2-8°C

Quality Level

100

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Application

Ellagic acid was used in TLC and RP-HPLC analysis for determination of phytoconstituents content in Root Bark of Oroxylum indicum.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Commonly occurring plant polyphenol, inhibitor of glutathione S-transferase. Used for the assay of factor XIIa in plasma. Contact activation in blood coagulation.

General description

Ellagic acid is a dimeric derivative of gallic acid. It is a plant polyphenol which has properties like antioxident, anti-inflammatory, anticancer and antiatherosclerosis.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This compound is commonly found in plants of the genus: eucalyptus

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP0076
BCCM4660
BCCL3254
BCCK4071
BCCH9682

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Quantification of baicalein, chrysin, biochanin-A and ellagic acid in root bark of Oroxylum indicum by RP-HPLC with UV detection.
Zaveri, Maitreyi, Amit Khandhar, and Sunita Jain.
Eurasian Journal of Analytical Chemistry, 3.2, 245-257 (2008)
Quantification of baicalein, chrysin, biochanin-A and ellagic acid in root bark of Oroxylum indicum by RP-HPLC with UV detection
Zaveri, Maitreyi, Amit Khandhar, and Sunita Jain
Eurasian Journal of Analytical Chemistry, 245-257 (2008)
V Arulmozhi et al.
Colloids and surfaces. B, Biointerfaces, 110, 313-320 (2013-06-05)
Ellagic acid (EA), a naturally occurring polyphenolic compound is well documented for its anticancer property in numerous pre-clinical models. The properties like poor water solubility and limited oral bio-availability of ellagic acid has hampered its clinical applications. The present study
Bin Li et al.
Carbohydrate polymers, 92(2), 1443-1450 (2013-02-13)
Structurally varied, carboxyl-containing cellulose derivatives were evaluated for their ability to form amorphous solid dispersions (ASD) with ellagic acid (EA), in order to improve the solubility of this high-melting, poorly bioavailable, but highly bioactive natural flavonoid compound. ASDs of EA
Marjan Van Blerk et al.
Thrombosis and haemostasis, 113(1), 154-164 (2014-09-19)
The Belgian national External Quality Assessment Scheme performed a nationwide survey using lyophilised plasma samples spiked with dabigatran or rivaroxaban to demonstrate to the Belgian clinical laboratories how these drugs affect their routine coagulation assays prothrombin time (PT), activated partial
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