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Merck

31618

2-Naphthylamine

analytical standard

Synonym(s):

β-Naphthylamine, 2-Aminonaphthalene

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About This Item

Linear Formula:
C10H7NH2
CAS Number:
91-59-8
Molecular Weight:
143.19
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329753849
EC Number:
202-080-4
Beilstein/REAXYS Number:
3939429
MDL number:
MFCD00004112

Key Documents

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Product Name

2-Naphthylamine, analytical standard

InChI key

JBIJLHTVPXGSAM-UHFFFAOYSA-N

InChI

1S/C10H9N/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-7H,11H2

SMILES string

Nc1ccc2ccccc2c1

grade

analytical standard

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

bp

306 °C (lit.)

mp

111-113 °C (lit.)

density

1.061 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

Quality Level

100

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Application

2-Naphthylamine has been used as reference standard during isolation and identification of urinary metabolites using preparative thin-layer chromatography and gas-liquid chromatography/mass spectral analysis.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Disclaimer

Restricted to professional users. Attention − Avoid exposure − obtain special instructions before use.

General description

2-Naphthylamine is a carcinogenic aromatic amine which induces tumor in urinary bladder.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 1A

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM3097
BCCL3096
BCCG4049
BCCC2053
BCBZ3240

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Metabolic conversion of 1-and 2-nitronaphthalene to 1-and 2-naphthylamine in the rat.
Johnson, Dale E., and Herbert H. Cornish.
Toxicology and Applied Pharmacology, 46.3, 549-553 (1978)
Formation of urothelial and hepatic DNA adducts from carcinogen 2-naphthylamine.
Kadlubar FF
Carcinogenesis, 2(5), 467-470 (1981)
Dylan M Owen et al.
Nature communications, 3, 1256-1256 (2012-12-06)
Lipid microdomains are postulated to regulate many membrane-associated processes but have remained highly controversial. Here we provide the first direct evidence that the plasma membrane of intact, live cells is comprised of a sub-resolution mixture of approximately 76% ordered and
Weimei Sun et al.
The Journal of pharmacology and experimental therapeutics, 375(3), 510-521 (2020-10-10)
Inhibition of the serine protease enteropeptidase (EP) opens a new avenue to the discovery of chemotherapeutics for the treatment of metabolic diseases. Camostat has been used clinically for treating chronic pancreatitis in Japan; however, the mechanistic basis of the observed
Joanna M Kwiatek et al.
PloS one, 8(2), e52960-e52960 (2013-02-08)
Visualization and quantification of lipid order is an important tool in membrane biophysics and cell biology, but the availability of environmentally sensitive fluorescent membrane probes is limited. Here, we present the characterization of the novel fluorescent dyes PY3304, PY3174 and
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