50058
Glycine
100.0%, tested according to Ph. Eur.
Synonym(s):
Glycinum, Aminoacetic acid, Aminoethanoic acid, Glycocoll
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About This Item
Linear Formula:
NH2CH2COOH
CAS Number:
Molecular Weight:
75.07
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
200-272-2
MDL number:
Beilstein/REAXYS Number:
635782
Product Name
Glycine, tested according to Ph. Eur.
Quality Level
agency
tested according to Ph. Eur.
assay
100.0%
form
crystalline
color
white
pH
6.2
pKa (25 °C)
(1) 2.35, (2) 9.60, 2.35
mp
240 °C (dec.) (lit.)
application(s)
research use (small molecule)
SMILES string
NCC(O)=O
InChI
1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChI key
DHMQDGOQFOQNFH-UHFFFAOYSA-N
Biochem/physiol Actions
Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.
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ppe
Eyeshields, Gloves, type N95 (US)
flash_point_f
No data available
flash_point_c
No data available
Storage Class
11 - Combustible Solids
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Alexander Carvajal-González et al.
Brain : a journal of neurology, 137(Pt 8), 2178-2192 (2014-06-22)
The clinical associations of glycine receptor antibodies have not yet been described fully. We identified prospectively 52 antibody-positive patients and collated their clinical features, investigations and immunotherapy responses. Serum glycine receptor antibody endpoint titres ranged from 1:20 to 1:60 000.
Zoé Husson et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(28), 9418-9431 (2014-07-11)
The principal neurons of the cerebellar nuclei (CN), the sole output of the olivo-cerebellar system, receive a massive inhibitory input from Purkinje cells (PCs) of the cerebellar cortex. Morphological evidence suggests that CN principal cells are also contacted by inhibitory
Li-Chun Tu et al.
The EMBO journal, 32(24), 3220-3230 (2013-11-12)
Nuclear pore complexes (NPCs) mediate cargo traffic between the nucleus and the cytoplasm of eukaryotic cells. Nuclear transport receptors (NTRs) carry cargos through NPCs by transiently binding to phenylalanine-glycine (FG) repeats on intrinsically disordered polypeptides decorating the NPCs. Major impediments