RDD044
Imidazole
ReagentPlus®, 99%, Redi-Dri™, free-flowing
Synonym(s):
Glyoxaline; 1, 3-diazole, 1,3-Diaza-2,4-cyclopentadiene, Glyoxaline
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About This Item
Empirical Formula (Hill Notation):
C3H4N2
CAS Number:
Molecular Weight:
68.08
NACRES:
NA.21
UNSPSC Code:
12352005
Beilstein/REAXYS Number:
103853
MDL number:
vapor pressure
<1 mmHg ( 20 °C)
Quality Level
product line
ReagentPlus®, Redi-Dri™
assay
99%
form
powder
quality
free-flowing
pH
9-11 at 100 g/L (23 °C)
pKa (25 °C)
6.95
bp
256 °C (lit.)
mp
85-92 °C, 88-91 °C (lit.)
SMILES string
c1c[nH]cn1
InChI
1S/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5)
InChI key
RAXXELZNTBOGNW-UHFFFAOYSA-N
General description
Imidazole is a buffering agent employed in various research applications, with a pH 9 -11, it is often used to maintain a stable pH for protein samples. Imidazole is a heterocyclic compound with a five-membered planar ring that is amphoteric, highly polar, and commonly used for affinity chromatography. Its ability to bind to metal ions makes it particularly useful for purification and separation of proteins.
Application
Excellent for buffers in the range of pH 6.2-7.8
Imidazole is commonly used as a buffer component for purification of the histidine-tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).
Features and Benefits
- Redi-Dri packaging controls moisture for hygroscopic chemicals that commonly clump
- Anhydrous powder remains free-flowing and easy to use
- Safer to handle and weigh out for routine use in lab
- Eliminates clumps to maintain product moisture and quality
Other Notes
For additional information on our range of Biochemicals, please complete this form.
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
Redi-Dri is a trademark of Sigma-Aldrich Co. LLC
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1C
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
flash_point_f
293.0 °F - closed cup
flash_point_c
145 °C - closed cup
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Three-Dimensional Covalent Co-Assembly between Inorganic Supertetrahedral Clusters and Imidazolates.
Wu T, et al.
Angewandte Chemie (International Edition in English), 50(11), 2536-2539 (2011)
Cobalt imidazolate framework as precursor for oxygen reduction reaction electrocatalysts.
Ma S, et al.
Chemistry?A European Journal , 17(7), 2063-2067 (2011)
Pam M Van Ry et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 23(8), 1285-1297 (2015-06-09)
Duchenne muscular dystrophy (DMD) is a fatal neuromuscular disease caused by mutations in the dystrophin gene, leading to the loss of a critical component of the sarcolemmal dystrophin glycoprotein complex. Galectin-1 is a small 14 kDa protein normally found in skeletal