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40234

N,N-Dimethyldodecylamine N-oxide

Name: <I>N,N</I>-Dimethyldodecylamine <I>N</I>-oxide
Brand: SIGMA

BioXtra, ≥99.0% (NT)

Synonym(s):

DDAO, LDAO, Lauryldimethylamine N-oxide

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About This Item

Linear Formula:

CH₃(CH₂)₁₁N(O)(CH₃)₂

CAS Number:

1643-20-5

Molecular Weight:

229.40

UNSPSC Code:

12161902

NACRES:

NA.26

PubChem Substance ID:

57649946

EC Number:

216-700-6

Beilstein/REAXYS Number:

1769927

MDL number:

MFCD00002049

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Properties

Quality Level

200

description

non-ionic, sulfate (ICP): ≤ 50 mg/kg

product line

BioXtra

assay

≥99.0% (NT)

form

powder

mol wt

229.40 g/mol

technique(s)

protein quantification: suitable

impurities

≤0.03% peroxides (as H₂O₂)

CMC

1-2 mM

mp

132-133 °C (lit.)

anion traces

chloride (Cl^-): ≤100 mg/kg

cation traces

Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤100 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCC[N+](C)(C)[O-]

InChI

1S/C14H31NO/c1-4-5-6-7-8-9-10-11-12-13-14-15(2,3)16/h4-14H2,1-3H3

InChI key

SYELZBGXAIXKHU-UHFFFAOYSA-N

Description

General description

N,N-Dimethyldodecylamine N-oxide is a non-denaturing zwitterionic surfactant with a critical micelle concentration (CMC) of approximately 1 mM. It is used to solubilize proteins and to study the conformation and molecular interactions of macromolecules.

Application

N,N-Dimethyldodecylamine N-oxide has been used in the cell lysis and resuspension of cell pellets for western blot analysis.

pictograms

GHS05,GHS07,GHS09

signalword

Danger

hcodes

H302,H315,H318,H410

pcodes

P264 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Influence of N-dodecyl-N,N-dimethylamine N-oxide on the activity of sarcoplasmic reticulum Ca(2+)-transporting ATPase reconstituted into diacylphosphatidylcholine vesicles: efects of bilayer physical parameters.

J Karlovská et al.

Biophysical chemistry, 119(1), 69-77 (2005-10-15)

Sarcoplasmic reticulum Ca-transporting ATPase (EC 3.6.1.38) was isolated from rabbit white muscle, purified and reconstituted into vesicles of synthetic diacylphosphatidylcholines with monounsaturated acyl chains using the cholate dilution method. In fluid bilayers at 37 degrees C, the specific activity of

Inhibition of ATP hydrolysis by thermoalkaliphilic F1Fo-ATP synthase is controlled by the C terminus of the epsilon subunit.

Stefanie Keis et al.

Journal of bacteriology, 188(11), 3796-3804 (2006-05-19)

The F(1)F(o)-ATP synthases of alkaliphilic bacteria exhibit latent ATPase activity, and for the thermoalkaliphile Bacillus sp. strain TA2.A1, this activity is intrinsic to the F(1) moiety. To study the mechanism of ATPase inhibition, we developed a heterologous expression system in

Hydrogen ion titration of alkyldimethylamine oxides by 13C and 1H NMR and conventional methods.

Rie Kakehashi et al.

Journal of colloid and interface science, 289(2), 498-503 (2005-08-23)

In the hydrogen ion titration of micelles, the degree of ionization of the micelle at a given pH has to be evaluated to obtain a pKa value of micelles (Ka being the proton dissociation constant) at the pH. We compared

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