A8171
D-Ala-Leu-Lys-7-amido-4-methylcoumarin
≥95% (HPLC)
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About This Item
Empirical Formula (Hill Notation):
C25H37N5O5
CAS Number:
Molecular Weight:
487.59
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
MDL number:
InChI
1S/C25H37N5O5/c1-14(2)11-20(30-23(32)16(4)27)25(34)29-19(7-5-6-10-26)24(33)28-17-8-9-18-15(3)12-22(31)35-21(18)13-17/h8-9,12-14,16,19-20H,5-7,10-11,26-27H2,1-4H3,(H,28,33)(H,29,34)(H,30,32)
SMILES string
CC(C)CC(NC(=O)C(C)N)C(=O)NC(CCCCN)C(=O)Nc1ccc2C(C)=CC(=O)Oc2c1
InChI key
FHYIXLQAMONDNN-UHFFFAOYSA-N
assay
≥95% (HPLC)
form
powder
solubility
water: 1 mg/mL, clear, colorless
storage temp.
−20°C
Quality Level
General description
Fluorogenic substrate for plasmin.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Direct photometric or fluorometric assay of proteinases using substrates containing 7-amino-4-trifluoromethylcoumarin.
R E Smith et al.
Thrombosis research, 17(3-4), 393-402 (1980-02-01)
María D Valls et al.
Frontiers in pharmacology, 12, 654104-654104 (2021-05-15)
Adenosine A2A receptor mediates the promotion of wound healing and revascularization of injured tissue, in healthy and animals with impaired wound healing, through a mechanism depending upon tissue plasminogen activator (tPA), a component of the fibrinolytic system. In order to
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