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B4639

Biotin

Name: Biotin
Brand: SIGMA

powder, BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, ≥99%

Synonym(s):

D-Biotin, Bios II, Coenzyme R, Vitamin B7, Vitamin H

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About This Item

Empirical Formula (Hill Notation):

C₁₀H₁₆N₂O₃S

CAS Number:

58-85-5

Molecular Weight:

244.31

NACRES:

NA.21

PubChem Substance ID:

24891795

eCl@ss:

34058011

UNSPSC Code:

12352201

EC Number:

200-399-3

MDL number:

MFCD00005541

Beilstein/REAXYS Number:

86838

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Properties

product line

BioReagent

Quality Level

200

assay

≥99%

form

powder

mol wt

M_w 244.31 g/mol

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable, cell culture | plant: suitable

color

white to off-white

mp

231-233 °C (lit.)

solubility

H₂O: 0.2 mg/mL (Solubility increases with addition of 1 N NaOH.)

storage temp.

2-8°C

SMILES string

[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2

InChI

1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1

InChI key

YBJHBAHKTGYVGT-ZKWXMUAHSA-N

Description

General description

Biotin is also called as B complex vitamin. It is a bicyclic compound, which has a molecular weight of 244.31 Da. Biotin serves as an important cofactor for mammalian carboxylases. It is found within the cells in free and bound pools.

Application

Biotin has been used:

as a M199 media supplement in in vitro culture system
as a component of SATO serum free medium for the isolation of cortical oligodendrocyte precursors (OPCs)
in biochemical precursors culture for de novo fatty acid synthesis
as a component in aggregate culture media

Biochem/physiol Actions

Essential vitamin that is important for amino acid and energy metabolism, and fatty acid synthesis. It is a prosthetic group in four mammalian carboxylase families and facilitates the binding and transfer of carbon dioxide.

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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number

0000548003

0000522963

0000522961

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