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Merck

D1538

Piperazine diacrylamide

For acrylamide gel electrophoresis

Synonym(s):

1,4-Bis(acryloyl)piperazine, 1,4-Di(acryloyl)piperazine, N,N′-Bis(acryloyl)piperazine, BAP, PDA, Piperazine diacrylamide

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About This Item

Empirical Formula (Hill Notation):
C10H14N2O2
CAS Number:
6342-17-2
Molecular Weight:
194.23
UNSPSC Code:
12352200
NACRES:
NA.52
PubChem Substance ID:
24893477
MDL number:
MFCD00077661
Beilstein/REAXYS Number:
745431

Key Documents

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Quality Level

200

InChI key

YERHJBPPDGHCRJ-UHFFFAOYSA-N

SMILES string

C=CC(=O)N1CCN(CC1)C(=O)C=C

InChI

1S/C10H14N2O2/c1-3-9(13)11-5-7-12(8-6-11)10(14)4-2/h3-4H,1-2,5-8H2

grade

Molecular Biology

product line

BioReagent

form

powder

technique(s)

electrophoresis: suitable

mp

91.5-93.5 °C (lit.)

storage temp.

room temp

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General description

1,4-Bis(acryloyl)piperazine is a reagent that can be substituted for bis-acrylamide in the preparation of polyacrylamide gels.

Application

Suitable for preparation of gels for PAGE, IEF, 2D electrophoresis and protein sequencing.

Features and Benefits

  • increases the gel strength and resolution
  • reduces background for silver background
  • can be substituted for bisacrylamide without changing polymerization protocol

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SLCM5490
SLCL9791
SLCL5632
SLCL2389
SLCF8899

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Ronaldo de Carvalho Augusto et al.
PLoS neglected tropical diseases, 11(7), e0005789-e0005789 (2017-07-29)
Schistosomiasis has been reported in 78 endemic countries and affects 240 million people worldwide. The digenetic parasite Schistosoma mansoni needs fresh water to compete its life cycle. There, it is susceptible to soluble compounds that can affect directly and/or indirectly
G Artoni et al.
Analytical biochemistry, 137(2), 420-428 (1984-03-01)
The properties of gels prepared either from acryloyl-morpholine (ACM) or from its mixtures with acrylamide and crosslinked either with bisacrylylpiperazine or with methylenebisacrylamide have been described. ACM-containing gels are compatible with organic solvents. If polymerized in water and dried, they
Su-Hyung Hong et al.
Biomarker insights, 1, 175-183 (2008-09-05)
Pancreatic cancer has a poor prognosis, in part due to lack of early detection. The identification of circulating tumor antigens or their related autoantibodies provides a means for early cancer diagnosis. We have used a proteomic approach to identify proteins
B Dupuy et al.
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology, 19(4), 667-674 (1991-01-01)
Activation of the complement system in vitro by a series of microcapsules based on polylysine, alginate or polyacrylamide was determined. Least activation was observed with microcapsules whose outer layer was composed of polyacrylamide. Activation was further reduced using diacrylylpiperazine instead
S A Piletsky et al.
Journal of molecular recognition : JMR, 11(1-6), 94-97 (1999-03-17)
A novel molecularly imprinted polymer (MIP) system selective for D-phenylalanine is described where polymerization is performed in aqueous solution. The unique polymer system comprises a hydrophobic moiety-selective functional monomer, polymerizable beta-cyclodextrin, an electrostatic interacting functional monomer, 2-acryloylamido-2-methylpropane sulfonic acid (AMPSA)
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