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Merck

P1584

Peptidyl Arginine Deiminase from rabbit skeletal muscle

buffered aqueous glycerol solution, ≥200 units/mg protein (Bradford)

Synonym(s):

Protein arginine iminohydrolase

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About This Item

CAS Number:
EC Number:
UNSPSC Code:
12352204
NACRES:
NA.54
MDL number:
Specific activity:
≥200 units/mg protein (Bradford)
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form

buffered aqueous glycerol solution

Quality Segment

specific activity

≥200 units/mg protein (Bradford)

relevant disease(s)

arthritis (rheumatoid )

shipped in

dry ice

storage temp.

−70°C

General description

Peptidyl arginine deiminase is the enzyme that converts arginine into citrulline.

Application

Peptidyl arginine deiminase has been used in a study that assessed promising novel biomarkers for the early diagnosis of rheumatoid arthritis. It has also been used in a study to investigate the autopathogenic correlation of periodontitis and rheumatoid arthritis.

Biochem/physiol Actions

Calcium is required for peptidylarginine deiminase activity in vitro.

Physical form

Solution in 20 mM Tris-HCl, pH 7.4, containing 10 mM 2-mercaptoethanol, 1 mM EDTA and 10% glycerol

Other Notes

One unit will produce 1 μmole of N-α-benzoylcitrulline ethyl ester from BAEE per hr at 55 °C at pH 7.2.


pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



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